8-AZAGUANINE

8-AZAGUANINE
  • CAS No.:134-58-7
Other grades of this product :
8-AZAGUANINE Basic information
Product Name:8-AZAGUANINE
Synonyms:2-Amino-6-hydroxy-8-azapurine, 2-Amino-6-oxy-8-azapurine, Guanazolo;5-aMino-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyriMidin-7-one;5-AMino-1H-[1,2,3]triazolo[4,5-d]pyriMidin-7(6H)-one;5-aMino-3H-[1,2,3]triazolo[4,5-d]pyriMidin-7(6H)-one;8-Azaguanine ,99%;8-Azaguanine,2-Amino-6-hydroxy-8-azapurine, 2-Amino-6-oxy-8-azapurine, 8-AzaG, Guanazolo;7H-1,2,3-Triazolo[4,5-d]pyriMidin-7-one, 5-aMino-3,6-dihydro-;5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL
CAS:134-58-7
MF:C4H4N6O
MW:152.11
EINECS:205-148-1
Product Categories:Nucleic acids;Pharmaceutical Raw Materials;Pyridines, Pyrimidines, Purines and Pteredines;Biochemistry;Nucleobases and their analogs;Nucleosides, Nucleotides & Related Reagents
Mol File:134-58-7.mol
8-AZAGUANINE Chemical Properties
Melting point >300 °C(lit.)
Boiling point 274.55°C (rough estimate)
density 1.5579 (rough estimate)
refractive index 2.3000 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pKa6.75±0.20(Predicted)
form lyophilized powder
Merck 896
InChIKeyLPXQRXLUHJKZIE-UHFFFAOYSA-N
CAS DataBase Reference134-58-7(CAS DataBase Reference)
NIST Chemistry Reference8-Azaguanine(134-58-7)
EPA Substance Registry System8-Azaguanine (134-58-7)
Safety Information
Hazard Codes Xn
Risk Statements 22
Safety Statements 22-24/25
WGK Germany 3
RTECS XZ6157000
10-23
HS Code 29335990
ToxicityLD50 oral in mouse: 1500mg/kg
MSDS Information
ProviderLanguage
SigmaAldrich English
8-AZAGUANINE Usage And Synthesis
Chemical Propertiesyellow powder
UsesAntineoplastic;Purine antimetabolite
Uses8-Azaguanine, is a purine analogue which shows antineoplastic activity.
DefinitionChEBI: A triazolopyrimidine that consists of 3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidine bearing amino and oxo substituents at positions 5 and 7 respectively.
HazardMitotoic poison.
Purification MethodsDissolve it in hot M NH4OH, filter, and cool. Recrystallise it, and wash it with water, then dry it in a vacuum. [Beilstein 26 III/IV 4171.]
8-AZAGUANINE Preparation Products And Raw materials
Raw materialsSodium dithionite-->Congo Red-->2,4-Diamino-6-hydroxypyrimidine ,98%

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