2-Amino-2',5-dichlorobenzophenone

CAS No.：2958-36-3

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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2-Amino-2',5-dichlorobenzophenone Basic information

Product Name:	2-Amino-2',5-dichlorobenzophenone
Synonyms:	(2-AMINO-5-CHLOROPHENYL)(2-CHLOROPHENYL)METHANONE;2'-AMINO-5'-CHLOROBENZOYL-2-CHLOROBENZENE;2-AMINO-5-CHLORO-2'-CHLOROBENZOPHENONE;2-AMINO-2',5-DICHLOROBENZOPHENONE;LABOTEST-BB LT00080738;LORAZEPAM IMP A;LORAZEPAM IMPURITY A;2-Amino-2',5-dichlorobenzophenone,99%
CAS:	2958-36-3
MF:	C13H9Cl2NO
MW:	266.12
EINECS:	220-985-2
Product Categories:	Aromatic Benzophenones & Derivatives (substituted);Benzene series;Cloxazolam;Benzophenones (for High-Performance Polymer Research);Functional Materials;Reagent for High-Performance Polymer Research;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;C13 to C14;Carbonyl Compounds;Ketones
Mol File:	2958-36-3.mol

2-Amino-2',5-dichlorobenzophenone Chemical Properties

Melting point	87-89 °C(lit.)
Boiling point	453.6±40.0 °C(Predicted)
density	1.3134 (rough estimate)
vapor pressure	0Pa at 25℃
refractive index	1.5490 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	methanol: soluble
form	neat
pka	-0.97±0.10(Predicted)
color	Yellow to Green
Water Solubility	Insoluble in water.
BRN	652774
InChIKey	KWZYIAJRFJVQDO-UHFFFAOYSA-N
LogP	3.1
CAS DataBase Reference	2958-36-3(CAS DataBase Reference)
NIST Chemistry Reference	Methanone, (2-amino-5-chlorophenyl)(2-chlorophenyl)-(2958-36-3)
EPA Substance Registry System	Methanone, (2-amino-5-chlorophenyl)(2-chlorophenyl)- (2958-36-3)

Safety Information

Hazard Codes	Xi,Xn
Risk Statements	36/37/38-20/21/22
Safety Statements	26-37/39-24/25-36
WGK Germany	3
RTECS	DJ0200000
Hazard Note	Irritant
TSCA	Yes
HS Code	29223900

MSDS Information

Provider	Language
2-Amino-2',5-dichlorobenzophenone	English
ACROS	English
SigmaAldrich	English
ALFA	English

2-Amino-2',5-dichlorobenzophenone Usage And Synthesis

Chemical Properties	YELLOW TO YELLOW-GREEN POWDER
Uses	2-Amino-2',5-dichlorobenzophenone is used to produce lorazepam a drug of the benzodiazepine group, used especially to treat anxiety.
Uses	Lorazepam Impurity A.
General Description	2-Amino-2′,5-dichlorobenzophenone can be synthesized from a precursor diazepine, Iorazepam.

2-Amino-2',5-dichlorobenzophenone Preparation Products And Raw materials

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