Centchroman

Centchroman
  • CAS No.:31477-60-8
Other grades of this product :
Centchroman Basic information
Product Name:Centchroman
Synonyms:Centchroman;1-[2-[p-(trans-7-Methoxy-2,2-diMethyl-3-phenyl- 4-chroManyl)phenoxy]ethyl]pyrrolidine;3,4-trans-2,2-DiMethyl-3-phenyl-4-[p-(β- py;rel-1-[2-[4-[(3R,4R)-3,4-dihydro-7-Methoxy-2,2-diMethyl-3-phenyl-2H-1-benzopyran-4-yl]phenoxy]ethyl]pyrrolidine;Pyrrolidine, 1-[2-[4-[(3R,4R)-3,4-dihydro-7-methoxy-2,2-dimethyl-3-phenyl-2H-1-benzopyran-4-yl]phenoxy]ethyl]-, rel-;Centchroman ISO 9001:2015 REACH
CAS:31477-60-8
MF:C30H35NO3
MW:457.6
EINECS:256-846-9
Product Categories:Aromatics;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:31477-60-8.mol
Centchroman Chemical Properties
Melting point 99-101°
Boiling point 563.39°C (rough estimate)
density 1.1065 (rough estimate)
refractive index 1.6310 (estimate)
storage temp. 2-8°C
form oil
pka9.61±0.20(Predicted)
color colorless to light brown
Safety Information
MSDS Information
Centchroman Usage And Synthesis
DescriptionCentchroman is a new, weekly, orally active contraceptive with weak estrogenic and potent antiestrogenic properties.It is reported to be the first non-hormonal, non-steroidal oral contraceptive. Centchroman acts by inhibiting the implantation of fertilized eggs in the uterus. With the exception of longer menstrual cycles, no side effects have been reported. Another indication under study is the treatment of hormone dependent breast cancer.
OriginatorCentral Drug Research Institute (India)
UsesCentchroman is an estrogen antagonist. Centchroman is a synthetic nonsteroidal postcoital antifertility agent.
Brand nameChoice-7
Centchroman Preparation Products And Raw materials
Preparation ProductsTolterodine-->Amlexanox

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