Other grades of this product :
| Sodium orthovanadate Basic information |
| Sodium orthovanadate Chemical Properties |
| Hazard Codes | Xn | | Risk Statements | 20/21/22 | | Safety Statements | 22-36 | | RIDADR | UN3285 | | WGK Germany | 3 | | RTECS | YW1120000 | | TSCA | Yes | | HazardClass | 6.1 | | PackingGroup | III | | HS Code | 28419030 |
| Sodium orthovanadate Usage And Synthesis |
| Chemical Properties | white to off-white powder | | Uses | Sodium orthovanadate is an alkaline phosphatase and (Na,K)-ATPase inhibitor with IC50 of 10 μM. | | Uses | Sodium Orthovanadate is an inhibitor of several phosphatases and kinases. General inhibitor of tyrosine phosphatases, a large family of enzymes that catalyze the removal of phosphate groups from tyrosine residues. | | Uses | Sodium orthovanadate (Na3VO4) can be used as a metal precursor in the synthesis of:Vanadium-MCM-48 (V-MCM-48) by anion-exchange method. V-MCM-48 is used as a catalyst in oxidation of styrene to benzaldehyde.Nanorods of vanadium oxide particles by glycothermal method.Yttrium vanadate (YVO4) doped with colloidal europium. | | Hazard | Poison by ingestion.
| | Biological Activity | Inhibitor of protein tyrosine phosphatases, alkaline phosphatases and ATPases. | | Biochem/physiol Actions | Sodium orthovandate suppresses the activation of p53-mediated apoptosis triggered in response to radiation. It reduces the detrimental effects of hematopoietic syndrome, hematopoiesis and delayed genotoxic effects of induced by total body irradiation of mice.24 In combination with menadione, orthovandate prevents the migration of detached human glioma cells in response to anti-cancer drugs.25 | | Safety Profile | Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of VOx and NazO. See also VANADIUM COMPOUNDS. |
| Sodium orthovanadate Preparation Products And Raw materials |
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