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| 1-(TOLUENE-4-SULFONYL)-1,2,3,4-TETRAHYDROBENZO[B]AZEPIN-5-ONE Basic information |
| Product Name: | 1-(TOLUENE-4-SULFONYL)-1,2,3,4-TETRAHYDROBENZO[B]AZEPIN-5-ONE | | Synonyms: | 1,2,3,4-Tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one;1-Tosyl-2,3,4,5-tetrahydro-1H-1-benzazepine-5-one;1-Tosyl-2,3-dihydro-1H-1-benzazepine-5(4H)-one;1-(TOLUENE-4-SULFONYL)-1,2,3,4-TETRAHYDROBENZO[B]AZEPIN-5-ONE;1-[(4-methylphenyl)sulfonyl]-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one;1-[(4-Methylbenzene)sulfonyl]-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one;1,2,3,4-tetrahydro-1-tosylbenzo[b]azepin-5-one;1,2,3,4-tetrahydro-1-(4-Methylbenzenesulfonyl)-1-benzazepin-5-one | | CAS: | 24310-36-9 | | MF: | C17H17NO3S | | MW: | 315.39 | | EINECS: | 1312995-182-4 | | Product Categories: | pharmacetical | | Mol File: | 24310-36-9.mol |
| 1-(TOLUENE-4-SULFONYL)-1,2,3,4-TETRAHYDROBENZO[B]AZEPIN-5-ONE Chemical Properties |
| Melting point | 126 °C(Solv: methanol (67-56-1)) | | Boiling point | 489.7±48.0 °C(Predicted) | | density | 1.286±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | pka | -3?+-.0.20(Predicted) |
| 1-(TOLUENE-4-SULFONYL)-1,2,3,4-TETRAHYDROBENZO[B]AZEPIN-5-ONE Usage And Synthesis |
| Uses | 1,2,3,4-Tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one is an intermediate used to prepare nonpeptide vasopressin V2 receptor antagonist tetrahydro-1H-benzazepines. It is also used to synthesize 4''-[(4,4-difluoro-5-methylidene-2,3,4,5-tetrahydro-1H-1-benzoazepin-1-yl)carbonyl]-2-phenylbenzanilide derivatives as non-peptide arginine vasopressin antagonists for both V1A and V2 receptors. |
| 1-(TOLUENE-4-SULFONYL)-1,2,3,4-TETRAHYDROBENZO[B]AZEPIN-5-ONE Preparation Products And Raw materials |
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![1-(TOLUENE-4-SULFONYL)-1,2,3,4-TETRAHYDROBENZO[B]AZEPIN-5-ONE](/img/24310-36-9.jpg "1-(TOLUENE-4-SULFONYL)-1,2,3,4-TETRAHYDROBENZO[B]AZEPIN-5-ONE")
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