4-Pyridinemethaneamine

CAS No.：3731-53-1

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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4-Pyridinemethaneamine Basic information

Product Name:	4-Pyridinemethaneamine
Synonyms:	4-Pyridylmethylamine, 95+%;4-PICOLYLAMINE 98+%;4-AMINOMETHYL PYRIDINE C-PYRIDIN-4-YL-METHYLAMINE;4-(AMINOMETHYL)PYRIDINE (4-PICOLYLAMINE);(Pyridin-4-yl)methylamine;4-(Aminomethyl)pyridine, 97+%;4-(Aminomethyl)pyridine, 98+%;4-Pyridylmethanamine
CAS:	3731-53-1
MF:	C6H8N2
MW:	108.14
EINECS:	223-092-6
Product Categories:	Others;Building Blocks;C6;Heterocyclic Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;API intermediates;Pyridines
Mol File:	3731-53-1.mol

4-Pyridinemethaneamine Chemical Properties

Melting point	−8 °C(lit.)
Boiling point	230 °C(lit.)
density	1.065 g/mL at 25 °C(lit.)
vapor pressure	10.4Pa at 25℃
refractive index	n20/D 1.552(lit.)
Fp	227 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform, Ethyl Acetate
form	Oil
pka	7.81±0.29(Predicted)
color	Clear Pale Yellow to Light Brown
Water Solubility	1000g/L at 20℃
Sensitive	Air Sensitive
BRN	108057
InChIKey	TXQWFIVRZNOPCK-UHFFFAOYSA-N
LogP	-0.38
CAS DataBase Reference	3731-53-1(CAS DataBase Reference)
NIST Chemistry Reference	4-(Aminomethyl)pyridine(3731-53-1)
EPA Substance Registry System	4-Pyridinemethanamine (3731-53-1)

Safety Information

Hazard Codes	C,Xi
Risk Statements	34-37-36/37/38
Safety Statements	26-36/37/39-45-36
RIDADR	UN 2735 8/PG 2
WGK Germany	3
TSCA	Yes
HazardClass	8
PackingGroup	III
HS Code	29333999

MSDS Information

Provider	Language
4-Pyridinemethaneamine	English
SigmaAldrich	English
ALFA	English

4-Pyridinemethaneamine Usage And Synthesis

Chemical Properties	Clear Light Brown Oil
Uses	4-(Aminomethyl)pyridine is a compound that has derivatives that act as reversible inhibitors of various copper amine oxidases (CAOs).
Synthesis Reference(s)	Chemical and Pharmaceutical Bulletin, 21, p. 1927, 1973 DOI: 10.1248/cpb.21.1927

4-Pyridinemethaneamine Preparation Products And Raw materials

Raw materials	Tetrahydrofuran-->Dichloromethane-->Acetic acid-->Potassium carbonate-->Ammonia-->Sodium bicarbonate-->Lithium Aluminum Hydride-->Hydrogen bromide-->4-Cyanopyridine-->Pyridinium dichromate
Preparation Products	4-Pyridylcarbinol-->ABC294640-->4-Pyridinealdoxime-->4-(BOC-AMINOMETHYL)PYRIDINE

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