Epifluorohydrin

Epifluorohydrin
  • CAS No.:503-09-3
Other grades of this product :
Epifluorohydrin Basic information
Product Name:Epifluorohydrin
Synonyms:(fluoromethyl)oxirane;1,2-epoxy-3-fluoro-propan;1-fluoro-2,3-epoxypropane;2-(Fluoromethyl)oxirane;3-Fluoropropene-1,2-oxide;Epifluorhydrine;Propane, 1,2-epoxy-3-fluoro-;3-Fluoro-1,2-propenoxide 99%
CAS:503-09-3
MF:C3H5FO
MW:76.07
EINECS:207-960-1
Product Categories:Contact Printing;Fluorine-Containing Monomers for 157 nm UV Lithography Resist Polymers;Lithography Monomers;Self Assembly &Building Blocks;Chemical Synthesis;Epoxides;Fluorinated Building Blocks;Heterocyclic Fluorinated Building Blocks;Materials Science;Micro/NanoElectronics;Organic Building Blocks;Other Fluorinated Heterocycles;Oxygen Compounds;monomer
Mol File:503-09-3.mol
Epifluorohydrin Chemical Properties
Boiling point 85-86 °C (lit.)
density 1.067 g/mL at 25 °C (lit.)
refractive index n20/D 1.368(lit.)
Fp 40 °F
storage temp. 0-6°C
CAS DataBase Reference503-09-3(CAS DataBase Reference)
NIST Chemistry ReferenceOxirane, (fluoromethyl)-(503-09-3)
EPA Substance Registry SystemEpifluorohydrin (503-09-3)
Safety Information
Hazard Codes F,T
Risk Statements 11-23/24/25-34
Safety Statements 16-26-45-38-36/37/39-33
RIDADR UN 2924 3/PG 2
WGK Germany 3
RTECS TZ3325000
Hazard Note Flammable/Highly Toxic
HazardClass 6.1(a)
PackingGroup I
HS Code 2910900090
MSDS Information
ProviderLanguage
Epifluorohydrin English
SigmaAldrich English
ACROS English
Epifluorohydrin Usage And Synthesis
Chemical Propertiesclear colourless liquid
UsesEpifluorohydrin is used as a reagent in the synthesis of N-arylphosphoramidates. In addition, it is used in the synthesis of orally bioavailable ALK inhibitors in the treatment of tumors.
General DescriptionClear colorless liquid.
Air & Water ReactionsHighly flammable. Water soluble.
Reactivity ProfileA halogenated epoxide. Epoxides are highly reactive. They polymerize in the presence of catalysts or when heated. These polymerization reactions can be violent. Compounds in this group react with acids, bases, and oxidizing and reducing agents. They react, possibly violently with water in the presence of acid and other catalysts. The chlorinated derivative has been shown to be incompatible with aniline, strong oxidizers, sulfuric acid, isopropylamine, zinc, aluminum, iron, etc. see epichlorohydrin.
Health HazardACUTE/CHRONIC HAZARDS: Epifluorohydrin is a lacrimator. When heated to decomposition it emits toxic fumes.
Fire HazardEpifluorohydrin is flammable.

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