CYTOCHALASIN C

CYTOCHALASIN C
  • CAS No.:22144-76-9
Other grades of this product :
CYTOCHALASIN C Basic information
Product Name:CYTOCHALASIN C
Synonyms:(11)cytochalasa-5,13,19-triene-1,17-dione,21-(acetoxy)-7,18-dihydroxy-16,18-di;(7s,13e,16s,18r,19e,21r)-methyl-10-phenyl;CYTOCHALASIN C;cytochalasin C from metarrhizium anisopliae;cytochalasin-C from metarrhizium*anisopliae;CYTOCHALASIN C(RG);7(S),18-dihydroxy-16(S),18(R)-dimethyl-10-phenyl[11]cytochalasa-5,13(E),19(E)-triene-1,17-dione 21(R)-acetate;CYTOCHALASIN C FROM METARRHIRIUM ANISOPL IAE
CAS:22144-76-9
MF:C30H37NO6
MW:507.62
EINECS:244-803-6
Product Categories:antibiotic;Enzyme Inhibitors;Enzyme Inhibitors by Type;Other
Mol File:22144-76-9.mol
CYTOCHALASIN C Chemical Properties
Melting point 260-264°C
Boiling point 595.84°C (rough estimate)
density 1.1764 (rough estimate)
refractive index 1.6310 (estimate)
storage temp. −20°C
solubility methylene chloride: 5 mg/mL, clear, colorless
form White to off-white powder.
pka11.95±0.70(Predicted)
BRN 1613194
Safety Information
Hazard Codes T+,T
Risk Statements 26/27/28-63
Safety Statements 28-36/37-45
RIDADR UN 1544 6.1/PG 2
WGK Germany 3
RTECS HA5300500
10
HazardClass 6.1(a)
PackingGroup I
HS Code 29337900
MSDS Information
ProviderLanguage
SigmaAldrich English
CYTOCHALASIN C Usage And Synthesis
Chemical PropertiesWhite solid
UsesCytochalasin C is one of a family of potent mycotoxins produced by a range of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, resulting in pronounced morphogenic changes in animals and plants. The cytochalasins act by disrupting actin microfilaments and these effects are most noticeable by the inhibition of cell division.
UsesCytochalasin C, a fungal metabolite, is an analog of Cytochalasin D (C998700), an anti-hypertensive drug acting on human intestinal epithelial caco-2 cells. Also has activity in HMG-CoA reductase inhibitors used in the lowering of cholesterol. Actin inhibitor, actin polymerization inhibitor affecting cell movement, growth, phagocytosis and even secretion.
CYTOCHALASIN C Preparation Products And Raw materials

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