cis-Vaccenic acid

cis-Vaccenic acid
  • CAS No.:506-17-2

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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cis-Vaccenic acid Basic information
Product Name:cis-Vaccenic acid
Synonyms:11-OCTADECENOIC ACID, STANDARD FOR GC;(Z)-11-Octadecenoicacid;11-cis-Vaccenicacid=Vaccenicacid;cis-Vaccenic ac;cis-Vaccenic Acid, Synthetic;(Z)-Octadec-11-enoic acid;cis-11-Vaccenic acid;cis-11-Octad
CAS:506-17-2
MF:C18H34O2
MW:282.46
EINECS:
Product Categories:Fatty & Aliphatic Acids, Esters, Alcohols & Derivatives
Mol File:506-17-2.mol
cis-Vaccenic acid Chemical Properties
Melting point 14-15 °C(lit.)
Boiling point 150 °C0.03 mm Hg(lit.)
density 0.887 g/mL at 25 °C(lit.)
refractive index n20/D 1.459(lit.)
Fp 230 °C
storage temp. -20°C
solubility Chloroform (Slightly), Ethanol (Soluble), Methanol (Slightly)
form oil
pka4.78±0.10(Predicted)
BRN 1726565
Stability:Light Sensitive, Volatile
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
F 8-10
MSDS Information
ProviderLanguage
SigmaAldrich English
cis-Vaccenic acid Usage And Synthesis
DescriptionVaccenic acid is an omega-7 fatty acid. It is a naturally occurring trans-fatty acid found in the fat of ruminants and in dairy products such as milk, butter, and yogurt. It is also the predominant fatty acid comprising trans fat in human milk. Its IUPAC name is (E)-11-octadecenoic acid, and its lipid shorthand name is 18:1 trans-11. The name was derived from the Latin vacca (cow). Vaccenic acid was discovered in 1928 in animal fats and butter. It is the main trans fatty acid isomer present in milk fat. Mammals convert it into rumenic acid, a conjugated linoleic acid, where it shows anticarcinogenic properties. Its stereoisomer, cis-vaccenic acid, also an omega-7 fatty acid, is found in Sea Buckthorn (Hippophae rhamnoides) oil. Its IUPAC name is (Z)-11-octadecenoic acid, and its lipid shorthand name is 18:1 cis-11.
Uses(Z)-11-Octadecenoic Acid, is a natural 18:1 ω-7 fatty acid. It is readily incorporated into triglycerides in perfused liver.
Purification MethodsPurify the acid by fractional distillation under high vacuum or crystallisation form its melt in an inert atmosphere away from light. [Beilstein 2 I 198, 2 III 1384, 2 IV 1639.]
cis-Vaccenic acid Preparation Products And Raw materials

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