XPhos Pd G2

CAS No.：1310584-14-5

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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XPhos Pd G2 Basic information

Appearance Reaction

Product Name:	XPhos Pd G2
Synonyms:	Chloro(2-dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-aMino-1,1'-biphenyl-2-yl) palladiuM(II), Min. 98% [XPhos Palladacycle];Chloro(2-dicyclohexylphosphino-2',4',6'-triisopropyl-1,1'-biphenyl)[2-(2'-aMino-1,1'-biphenyl)]palladiuM(II);Chloro(2-dicyclohexylphosphin;(SP-4-4)-[2'-Amino[1,1'-biphenyl]-2-yl]chloro[dicyclohexyl[2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine]palladium;2nd Generation XPhos Precatalyst;X-Phos aminobiphenyl palladium chloride precatalyst;Palladium-Xphos;-biphenyl-2-yl) palladium(II), min. 98%
CAS:	1310584-14-5
MF:	C45H58ClNPPd+2
MW:	785.795481
EINECS:
Product Categories:	Pd;Buchwald Ligands&Precatalysts;Buchwald Precatalysts Series
Mol File:	1310584-14-5.mol

XPhos Pd G2 Chemical Properties

Melting point	202-210°C
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
form	Powder
color	white
InChIKey	USWOVTRTHZODCW-UHFFFAOYSA-N

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26
WGK Germany	3

MSDS Information

XPhos Pd G2 Usage And Synthesis

Appearance	Turquoise or grey or dark green powder
Reaction	Palladium precatalyst for Suzuki-Miyaura coupling reactions.
Uses	XPhos Pd G2 is a used as a catalyst in chemical reactions.
Uses	XPhos Pd G2 was employed as catalyst in the following reactions: Palladium-catalyzed Suzuki-Miyaura coupling reactions of potassium organotrifluoroborates and sulfamates. Suzuki-Miyaura cross-coupling reactions of sensitive aryl and heteroarylboronic acids. Synthesis of potassium Boc-protected secondary aminomethyltrifluoroborates, via Suzuki-Miyaura cross-coupling reaction.
General Description	XPhos Pd G2 is a bulky monodentate biaryl ligand. It is aBuchwald′s 2^nd generation preformed catalyst. It undergoesrapid reductive elimination to form a reactive, monoligated Pd(0) species.

XPhos Pd G2 Preparation Products And Raw materials

Raw materials

X-PHOS-->2-Aminobiphenyl

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