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| (R)-1-benzyl-5-methyl-1,4-diazepane Basic information |
| Product Name: | (R)-1-benzyl-5-methyl-1,4-diazepane | | Synonyms: | (R)-1-benzyl-5-methyl-1,4-diazepane;(5R)-1-benzyl-5-methyl-1,4-diazepane;Suvorexant intermediate (5R)-Hexahydro-5-methyl-1-(phenylmethyl)-1H-1,4-diazepine;Suvorexant (MK-4305) intermediate;(5R)-Hexahydro-5-methyl-1-(phenylmethyl)-1H-1,4-diazepine;1H-1,4-Diazepine, hexahydro-5-methyl-1-(phenylmethyl)-, (5R)-;(R)-1-benzyl-5-methyl-1,4-diazepane(For export only) | | CAS: | 1620097-06-4 | | MF: | C13H20N2 | | MW: | 204.31 | | EINECS: | | Product Categories: | | Mol File: | 1620097-06-4.mol |
| (R)-1-benzyl-5-methyl-1,4-diazepane Chemical Properties |
| Boiling point | 296.1±28.0 °C(Predicted) | | density | 0.974±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | pka | 10.65±0.40(Predicted) |
| (R)-1-benzyl-5-methyl-1,4-diazepane Usage And Synthesis |
| Uses | (5R)-1-Benzyl-5-methyl-1,4-diazepane is a synthetic substance with inhibitory activity on calcium channels. It has been shown to be useful for the treatment of epilepsy and other neurological disorders in animal models. | | Synthesis | The synthesis of (5R)-1-benzyl-5-methyl-1,4-diazepane was achieved by a two step process that involved the coupling of benzaldehyde and methyl vinyl ketone followed by the formation of an azide from methyl nitrite. This substance was purified using liquid chromatography and high performance liquid chromatography, which yielded a purity of 99%. A validation study confirmed that the impurities did not exceed 1% in concentration. |
| (R)-1-benzyl-5-methyl-1,4-diazepane Preparation Products And Raw materials |
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