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| 2-Fluoroadenosine Basic information |
| 2-Fluoroadenosine Chemical Properties |
| Melting point | 240 °C (D)(lit.) | | Boiling point | 747.3±70.0 °C(Predicted) | | density | 2.17±0.1 g/cm3(Predicted) | | refractive index | -72 ° (C=0.1, EtOH) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | DMSO (Slightly, Sonicated), Methanol (Slightly, Heated, Sonicated) | | form | Solid | | pka | 13.05±0.70(Predicted) | | color | Off-White | | CAS DataBase Reference | 146-78-1(CAS DataBase Reference) |
| Hazard Codes | Xn | | Risk Statements | 22-36/37/38 | | Safety Statements | 26 | | WGK Germany | 3 | | RTECS | AU7386000 | | HS Code | 29349990 |
| 2-Fluoroadenosine Usage And Synthesis |
| Description | 2-Fluoroadenosine (F-Ado) was developed at Southern Research Institute in 1957 as a potential anticancer drug. 2-Fluoroadenosine is not deaminated by adenosine deaminase but metabolized to triphosphate as shown in vitro. The drug was also shown to be a potent inhibitor of lymphocyte-mediated cytolysis. | | Uses | 2-Fluoroadenosine is a fluorinated analog of Adenoside nucleotide. It is used as an intermediate for the drug fludarabine. Fludarabine is a purine analogue and antineoplastic agent. It is a chemotherapy medication used in the treatment of leukemia and lymphoma. | | Definition | ChEBI: 2-fluoroadenosine is a member of adenosines and an organofluorine compound. |
| 2-Fluoroadenosine Preparation Products And Raw materials |
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