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| 10-Gingerol Basic information |
| 10-Gingerol Chemical Properties |
| Melting point | 56-58 °C | | Boiling point | 499.7±35.0 °C(Predicted) | | density | 1.037±0.06 g/cm3(Predicted) | | Fp | 166℃ | | storage temp. | 2-8°C | | solubility | methanol: soluble5mg/mL, clear, colorless | | form | neat | | pka | 10.02±0.20(Predicted) | | InChIKey | AIULWNKTYPZYAN-SFHVURJKSA-N |
| Risk Statements | 53 | | Safety Statements | 24/25 | | WGK Germany | 3 | | HS Code | 29145019 |
| 10-Gingerol Usage And Synthesis |
| Description | 10-Gingerol is a phenol that has been found in Z. officinale and has diverse biological activities. It scavenges DPPH , superoxide, and hydroxyl radicals in cell-free assays (IC50s = 10.47, 1.68, and 1.35 μM, respectively) and inhibits oxidative burst induced by N-formyl-Met-Leu-Phe (fMLP; ) in isolated human polymorphonuclear (PMN) neutrophils when used at a concentration of 6 μM. 10-Gingerol inhibits NETosis and the production of reactive oxygen species (ROS) induced by LPS or lupus-relevant stimuli, including ribonucleoprotein-containing immune complexes and anti-phospholipid antibodies, in isolated human neutrophils. It is active against M. avium and M. tuberculosis (MICs = 25 and 50 μg/ml, respectively). 10-Gingerol (200 μM) is also cytotoxic to human MDA-MB-231 and MDA-MB-468 and murine 4T1 and EO771 mammary carcinoma cells. | | Uses | (+)-(S)-[10]-Gingerol has been observed to exhibit anti-oxidant behaviour towards lipids and is effective in suppressing obesity and adipose tissue inflammation. | | Biochem/physiol Actions | [10]-Gingerol is a bioactive compound found in ginger (Zingiber officinale) with anti-inflammatory and antioxidant activity. |
| 10-Gingerol Preparation Products And Raw materials |
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