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| Product Name: | Diphenic acid | | Synonyms: | 2,2'-DIPHENIC ACID;2,2'-DIPHENYLDICARBOXYLIC ACID;2,2'-DICARBOXYBIPHENYL;2,2'-DICARBOXY DIPHENYL;2,2'-BIPHENYLDICARBOXYLIC ACID;2,2'-BIBENZOIC ACID;[1,1'-BIPHENYL]-2,2'-DICARBOXYLIC ACID;BIPHENYL-2,2'-DICARBOXYLIC ACID | | CAS: | 482-05-3 | | MF: | C14H10O4 | | MW: | 242.23 | | EINECS: | 207-576-4 | | Product Categories: | Biphenyl series;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Biphenyl & Diphenyl ether;Biphenyls (for High-Performance Polymer Research);Functional Materials;Reagent for High-Performance Polymer Research;FINE Chemical & INTERMEDIATES | | Mol File: | 482-05-3.mol |
| Diphenic acid Chemical Properties |
| Melting point | 227-229 °C(lit.) | | Boiling point | 345.05°C (rough estimate) | | density | 1.2695 (rough estimate) | | refractive index | 1.5389 (estimate) | | storage temp. | Store below +30°C. | | solubility | almost transparency in Methanol | | form | powder to crystal | | pka | pKa 3.20(H2O t=23.0) (Uncertain);5.06(H2O t=23.0) (Uncertain) | | color | White to Orange to Green | | PH | 4-5 (H2O, 20℃) | | Water Solubility | insoluble (20 ºC) | | Merck | 14,3310 | | BRN | 2053625 | | InChIKey | GWZCCUDJHOGOSO-UHFFFAOYSA-N | | CAS DataBase Reference | 482-05-3(CAS DataBase Reference) | | NIST Chemistry Reference | 2,2'-Biphenyldicarboxylic acid(482-05-3) | | EPA Substance Registry System | [1,1'-Biphenyl]-2,2'-dicarboxylic acid (482-05-3) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39-37 | | WGK Germany | 3 | | Autoignition Temperature | 390 °C | | TSCA | Yes | | HS Code | 29173980 |
| Diphenic acid Usage And Synthesis |
| Description | 2,2’Dicarboxybiphenyl acid is also known as diphenic acid, being a useful pharmaceutical intermediate and used in the synthesis of dyes. Diphenic acid derivatives have attracted great attention due to its possession of useful therapeutic properties. Many diphenic acids derivatives have the potential of lowering the risk of chronic diseases such as cancer, cardiovascular diseases and other pathologies. It is applied in many herbs and components of food. Diphenic acids derivatives can usually be found in fruits like blackberry, raspberry and strawberry.
| | Sources | https://www.alfa.com/zh-cn/catalog/A15863/
https://www.tandfonline.com/doi/abs/10.1080/00397911.2017.1298805?journalCode=lsyc20
| | Chemical Properties | Off-white powder | | Synthesis Reference(s) | Journal of the American Chemical Society, 82, p. 2876, 1960 DOI: 10.1021/ja01496a051Organic Syntheses, Coll. Vol. 1, p. 222, 1941Synthesis, p. 731, 1982 | | Purification Methods | Crystallise diphenic acid from water. Hot Ac2O provides the anhydride below. [Beilstein 9 H 922, 9 IV 3552.] |
| Diphenic acid Preparation Products And Raw materials |
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