4-PENTYNOIC ACID

4-PENTYNOIC ACID
  • CAS No.:6089-09-4
Other grades of this product :
4-PENTYNOIC ACID Basic information
Product Name:4-PENTYNOIC ACID
Synonyms:4-Pentynoic acid, 95&percnt:;Propargylacetic acid, 2-Propargylethanoic acid;Pent-4-yn-1-oic acid;pent-4-yn-1-oicacid;PROPARGYLACETIC ACID;4-PENTYNOIC ACID;TIMTEC-BB SBB009121;4-Pentynoicacid,98%
CAS:6089-09-4
MF:C5H6O2
MW:98.1
EINECS:228-028-0
Product Categories:Carboxylic Acids;Chemical Synthesis;Building Blocks;C1 to C5;Carbonyl Compounds;Organic Building Blocks;Aliphatics;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:6089-09-4.mol
4-PENTYNOIC ACID Chemical Properties
Melting point 54-57 °C(lit.)
Boiling point 110 °C30 mm Hg(lit.)
density 1.1133 (rough estimate)
refractive index 1.3930 (estimate)
Fp 75 °C
storage temp. 2-8°C
pka4.30±0.10(Predicted)
form Crystalline Powder or Flakes
color White to beige
Water Solubility Soluble in low polarity organic solvents. Soluble in water.
Sensitive Light & Air Sensitive & Hygroscopic
BRN 1742047
InChIKeyMLBYLEUJXUBIJJ-UHFFFAOYSA-N
CAS DataBase Reference6089-09-4(CAS DataBase Reference)
Safety Information
Hazard Codes C
Risk Statements 34
Safety Statements 26-36/37/39-45
RIDADR UN 3261 8/PG 2
WGK Germany 3
RTECS SC4751000
8-10-23
Hazard Note Corrosive
HazardClass 8
PackingGroup III
HS Code 29161900
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
4-PENTYNOIC ACID Usage And Synthesis
Chemical Propertieswhite to beige crystalline powder or flakes
Uses4-Pentynoic Acid is a hypoglycemic agent shown to increase liver tyrosine aminotransferase and plasma corticosterone while decreasing blood sugar in rats.
Uses4-Pentynoic acid was used:
  • as building block for the synthesis of library of eight sequence-defined model oligomers
  • in one-pot synthesis of the complex polycyclic heterocycles benzo[4,5]imidazo[1,2-c]pyrrolo[1,2-a]quinazolinone derivatives
  • in the synthesis of various allenenols lactones [5(E)-(2-allenylidene)-tetrahydro-2-furanones]
  • in the synthesis of a cyctotoxic macrolide by ring-closing metathesis of a bis acetylene
General Description4-Pentynoic acid undergoes copper-catalyzed intramolecular cyclizations to form enol lactones. It also reacts with 1-bromo-1-alkynes in the presence of a Pd catalyst to yield biologically active ynenol lactones.
4-PENTYNOIC ACID Preparation Products And Raw materials
Raw materialsHydrochloric acid-->Diethyl ether-->Sulfuric acid-->Sodium carbonate-->Magnesium sulfate-->Acetone-->Hexane-->Chromium(VI) oxide-->4-Pentyn-1-ol
Preparation Productsmethyl 3-oxohept-6-ynoate

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