3-CHLORO-L-ALANINE HYDROCHLORIDE

CAS No.：51887-89-9

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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3-CHLORO-L-ALANINE HYDROCHLORIDE Basic information

Product Name:	3-CHLORO-L-ALANINE HYDROCHLORIDE
Synonyms:	H-ALA(3-CL)-OH HCL;H-BETA-CHLORO-ALA-OH HCL;(R)-2-AMINO-3-CHLOROPROPIONIC ACID HYDROCHLORIDE;B-CHLORO-L-ALANINE HYDROCHLORIDE;3-Chloro-L-alanineHCl;β-chloro-l-alanine hydrochloride;3-CHLORO-L-ALANINE HYDROCHLORIDE 98+%;H-b-Chloro-Ala-OH·HCl
CAS:	51887-89-9
MF:	C3H7Cl2NO2
MW:	160
EINECS:	200-528-9
Product Categories:	Carboxylic Acids (Chiral);Chiral Building Blocks;Synthetic Organic Chemistry;A;AA to ALCertified Reference Materials (CRMs);Alphabetic;Application CRMs;Clinical Chemistry CRM;Alanine aminotransferase;Alanine aminotransferasePeptides for Cell Biology;A to;Enzyme Inhibitors;Enzyme Inhibitors by Enzyme
Mol File:	51887-89-9.mol

3-CHLORO-L-ALANINE HYDROCHLORIDE Chemical Properties

Melting point	205 °C (dec.)(lit.)
storage temp.	-20°C
form	powder to crystal
color	White to Almost white
InChIKey	IENJPSDBNBGIEL-DKWTVANSSA-N
CAS DataBase Reference	51887-89-9(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3

MSDS Information

Provider	Language
SigmaAldrich	English

3-CHLORO-L-ALANINE HYDROCHLORIDE Usage And Synthesis

Chemical Properties	White solid
Uses	β-Chloro-L-alanine hydrochloride has been used: as a substrate for screening tyrosine phenol lyase steady state kinetics in the inhibition of serine palmitoyltransferase and cytotoxicity studies in lymphocyte Ly-1 cells as an inhibitor of alanine transaminase in wheat germ cell-free protein synthesis system
Biochem/physiol Actions	β-Chloro-L-alanine hydrochloride is an inhibitor of alanine aminotransferase (ALAT). Inhibition of ALAT leads to suppression of tumor progression in lung carcinoma.

3-CHLORO-L-ALANINE HYDROCHLORIDE Preparation Products And Raw materials

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