Product

(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone

CAS No.：149249-91-2

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(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone Basic information

Product Name:	(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone
Synonyms:	(3R,4S)-1-Benzoyl-3-[(Triethyl;PACLITAXEL SIDE CHAIN/(3R,4S)-1-BENZOYL-3-[(TRIETHYLSILYL)OXY]-4-PHENYL-2-PHENYL-2-AZETIDINONE;PACLITAXEL SIDE CHAIN NO 2;(3R,4S)-1-Benzoyl-4-Phenyl-3-[(Triethylsilyl)Oxy]-2-AzetidinoneCasNo.;(3R,4S)-1-BENZOYL-3-[(TRIETHYLSILYS)OXY]-4-PHENYL-2-AZETIDINONE;(3R,4S)-3-triethylsilanyloxy-4-phenyl-N-benzoyl-2-azetidinone;(3R,4S)-1-benzoyl-4-phenyl-3- (triethylsilyloxy)azetidin-2-one;1-benzoyl-4-phenyl-3-triethylsilyloxy-2-azetidinone
CAS:	149249-91-2
MF:	C22H27NO3Si
MW:	381.54
EINECS:
Product Categories:
Mol File:	149249-91-2.mol

(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone Chemical Properties

Boiling point	467.2±55.0 °C(Predicted)
density	1.12
storage temp.	2-8°C
solubility	Dichloromethane, Ether, Ethyl Acetate, Methanol
form	Oil
pka	-4.66±0.60(Predicted)
color	Transparent
CAS DataBase Reference	149249-91-2(CAS DataBase Reference)

Safety Information

MSDS Information

(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone Usage And Synthesis

Uses

(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone is an intermedaite of 10-O-[(2R,3S)-3-(Benzoylamino)-2-hydroxy-3-phenylpropanoyl]-10-O-deacetylpaclitaxel (B207800), which is an impurity in the synthesis of Paclitaxel (P132500), an antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi''s sarcoma.

(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone Preparation Products And Raw materials

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