2,6-Dioxopiperidine-3-ammonium chloride

CAS No.：24666-56-6

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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2,6-Dioxopiperidine-3-ammonium chloride Basic information

Description

Product Name:	2,6-Dioxopiperidine-3-ammonium chloride
Synonyms:	2,6-Dioxopiperidine-3-ammonium chloride;2,6-Dioxopiperidine-3-ammonium;Lenalidomide Impurity 6 HCl;Pomalidomide/lenalidomide INT II;3-Amino-piperidine-2,6-dione [2353-44-8] at 262 USD, please be noted, what we provide is HCl salt form;2,6-dioxopiperidin-3-aminium chloride;Pomalidomide Impurity 6;6-piperidinedione hydrochloride
CAS:	24666-56-6
MF:	C5H9ClN2O2
MW:	164.59016
EINECS:	807-866-6
Product Categories:	Pyrrolidines
Mol File:	24666-56-6.mol

2,6-Dioxopiperidine-3-ammonium chloride Chemical Properties

Melting point	120 °C (approx)
storage temp.	Inert atmosphere,Room Temperature

Safety Information

Risk Statements	20/21/22
Safety Statements	3/9-36/37
HS Code	29339900

MSDS Information

2,6-Dioxopiperidine-3-ammonium chloride Usage And Synthesis

Description	2,6-Dioxopiperidine-3-ammonium chloride is a reagent for preparing lenalidomide that can induce ubiquitination and degradation of CK1α in del (5q) MDS. It can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation. Moreover, it is also a metabolite of thalidomide (T338850) that inhibits FGF-induced angiogenesis.
Chemical Properties	White crystal
Uses	2,6-Dioxopiperidine-3-ammonium chloride can be used as an important intermediate of antineoplastic drug lenalidomide.

2,6-Dioxopiperidine-3-ammonium chloride Preparation Products And Raw materials

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