2-(Trifluoromethyl)isonicotinic acid

2-(Trifluoromethyl)isonicotinic acid
  • CAS No.:131747-41-6
Other grades of this product :

2-(Trifluoromethyl)isonicotinic acid Basic information
Product Name:2-(Trifluoromethyl)isonicotinic acid
Synonyms:2-(Trifluoromethyl)pyridine-4-carboxylic acid, 4-Carboxy-2-(trifluoromethyl)pyridine;2-(TRIFLUOROMETHYL)ISONICOTINIC ACID;2-(Trifluoromethyl)pyridine-4-carBoxylicacid;2-(Trifluoromethyl)isonicotinicacid97%;2-trifluoromethyl-4-pyridinecarboxylic acid;2-(Trifluoromethyl)isonicotinic acid 97%;2-(trifluoroMethyl)pyridin-4-carboxylic acid;4-Pyridinecarboxylicacid, 2-(trifluoroMethyl)-
CAS:131747-41-6
MF:C7H4F3NO2
MW:191.11
EINECS:
Product Categories:Pyridine series;Carboxylic Acids;Pyridines;Carboxylic  Acids
Mol File:131747-41-6.mol
2-(Trifluoromethyl)isonicotinic acid Chemical Properties
Melting point 217-223℃
Boiling point 338.9±42.0 °C(Predicted)
density 1.484±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
form Solid
pka2.94±0.10(Predicted)
color Off-white
Water Solubility Slightly soluble in water.
CAS DataBase Reference131747-41-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 26-36/37/39
WGK Germany 3
HS Code 2933399990
MSDS Information
2-(Trifluoromethyl)isonicotinic acid Usage And Synthesis
Uses2-(Trifluoromethyl)isonicotinic Acid is useful reactant for the preparation of RAF709 as selective RAF inhibitor targeting RAS mutant cancer.
2-(Trifluoromethyl)isonicotinic acid Preparation Products And Raw materials
Raw materials3-Buten-2-one, 1,1,1-trifluoro-4-(2-furanyl)--->Pyridine, 4-(2-furanyl)-2-(trifluoromethyl)--->3-IODO-2-(TRIFLUOROMETHYL)PYRIDINE-->2-(TRIFLUOROMETHYL)-4-HYDROXYPYRIDINE-->2-Bromopyridine-4-carboxylic acid-->2-Trifluoromethyl-isonicotinonitrile-->4-Iodo-2-(trifluoromethyl)pyridine-->2-TRIFLUOROMETHYL-4-CHLOROPYRIDINE-->2-(Trifluoromethyl)pyridine-->carbon monoxide-->CARBON DIOXIDE-->Trimethylaluminium
Preparation Products2-Trifluoromethyl-6-pyridinecarboxylic acid

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