2-Thiopheneacetic acid

2-Thiopheneacetic acid
  • CAS No.:1918-77-0
Other grades of this product :
2-Thiopheneacetic acid Basic information
Product Name:2-Thiopheneacetic acid
Synonyms:Thiophene-2-acetic acid, 98+%;2-THIOPHENE-2-ACETIC ACID;2-Thiophene;2-(Thien-2-yl)acetic acid 97%;2-THIOPHENEACETIC ACID;2-THIENYLACETIC ACID;2-THENYLACETIC ACID;2-(2-Thienyl)acetic acid
CAS:1918-77-0
MF:C6H6O2S
MW:142.18
EINECS:217-639-8
Product Categories:Cephaloridine;Heterocycles;Drug Intermediates;Thiophene&Benzothiophene;Organic acids;Thiophens;thiophenes;bc0001
Mol File:1918-77-0.mol
2-Thiopheneacetic acid Chemical Properties
Melting point 63-64 °C (lit.)
Boiling point 160 °C/22 mmHg (lit.)
density 1.365 (estimate)
refractive index 1.5300 (estimate)
Fp 160°C/22mm
storage temp. Keep in dark place,Inert atmosphere,2-8°C
pka4.23±0.10(Predicted)
form Crystalline Powder
color Slightly brown to brown
Water Solubility Soluble in water, ethanol, ether and carbon tetrachloride.
BRN 114551
CAS DataBase Reference1918-77-0(CAS DataBase Reference)
NIST Chemistry Reference2-Thiopheneacetic acid(1918-77-0)
EPA Substance Registry System2-Thiopheneacetic acid (1918-77-0)
Safety Information
Hazard Codes C,Xi
Risk Statements 34-37-36/37/38
Safety Statements 26-36/37/39-45-24/25-27
RIDADR UN 3261 8/PG 2
WGK Germany 3
Hazard Note Irritant
TSCA T
HazardClass 8
PackingGroup III
HS Code 29349990
MSDS Information
ProviderLanguage
Thiophene-2-acetic acid English
ACROS English
SigmaAldrich English
ALFA English
2-Thiopheneacetic acid Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powder
Uses2-Thiopheneacetic acid is used in the preparation of rosette-like nanoscale gold materials. Further, it is used as a pharmaceutical intermediate for cefaloridine and cefalotin sodium.
Synthesis Reference(s)Canadian Journal of Chemistry, 46, p. 1057, 1968 DOI: 10.1139/v68-179Journal of the American Chemical Society, 72, p. 4326, 1950
General DescriptionAdsorption of 2-thiopheneacetic acid on XAD-4, NDA-100 and ND-90 resin has been investigated. A new polymeric complex of Cu(II) and 2-thiopheneacetic acid has been synthesized and characterized by IR and Raman spectroscopy.
Purification MethodsCrystallise the acid from ligroin, hexane and/or distil it in a vacuum. The amide has m 148o (from H2O or pet ether). [Beilstein 18 H 293, 18 III/IV 4062, 18/6 V 207.]

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