| 2,5-Dihydroxybenzaldehyde Basic information |
| Description synthesis |
| Product Name: | 2,5-Dihydroxybenzaldehyde |
| Synonyms: | GENTISALDEHYDE;GENTISIC ALDEHYDE;GENTISINALDEHYDE;5-HYDROXYSALICYLALDEHYDE;2,5-DIHYDROXYBENZALDEHYDE;Benzaldehyde, 2,5-dihydroxy-;2,5-Dihydroxybenzaldehyde, 98+%;2,5-Dihydroxybenzaldchyde |
| CAS: | 1194-98-5 |
| MF: | C7H6O3 |
| MW: | 138.12 |
| EINECS: | 214-789-6 |
| Product Categories: | 1;Aromatic Aldehydes & Derivatives (substituted);Aldehydes;Phenyls & Phenyl-Het;Benzaldehyde;Aromatics;Phenyls & Phenyl-Het;1194-98-5 |
| Mol File: | 1194-98-5.mol |
| 2,5-Dihydroxybenzaldehyde Chemical Properties |
| Melting point | 97-99 °C (lit.) |
| Boiling point | 213.5°C (rough estimate) |
| density | 1.2667 (rough estimate) |
| refractive index | 1.4797 (estimate) |
| storage temp. | Store below +30°C. |
| solubility | 13.8g/l soluble |
| pka | 8.89±0.18(Predicted) |
| form | Crystalline Powder |
| color | Yellow to khaki-green |
| Water Solubility | soluble |
| Sensitive | Air Sensitive |
| BRN | 1363961 |
| InChIKey | CLFRCXCBWIQVRN-UHFFFAOYSA-N |
| CAS DataBase Reference | 1194-98-5(CAS DataBase Reference) |
| NIST Chemistry Reference | 2,5-Dihydroxybenzaldehyde(1194-98-5) |
| EPA Substance Registry System | Benzaldehyde, 2,5-dihydroxy- (1194-98-5) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38-43 |
| Safety Statements | 26-36/37/39-37/39-26,37/39-36 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| TSCA | Yes |
| HS Code | 29124990 |
| MSDS Information |
| Provider | Language |
|---|---|
| 2,5-Dihydroxybenzaldehyde | English |
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| 2,5-Dihydroxybenzaldehyde Usage And Synthesis |
| Description | 2,5-Dihydroxybenzaldehyde is a building block. It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activity. |
| synthesis | Add 80 mmol of dry paraformaldehyde to a mixture of 12 mmol of the phenol derivative and 2.5 mmol of MgO nanocrystalline (0.1 g). Expose the resulting mixture under microwave irradiation with a power of 650 W. Monitor the progress of the reaction by thin layer chromatography (TLC) developed by n-hexane : ethyl acetate (8 : 2). Add 100 mL of sulfuric acid (15% w/w) to the reaction mixture and heated at 50 °C for 15 min. Cool the reaction mixture to room temperature. Extract the product by dichloromethane (2 x 50 mL). Dry the organic layer over anhydrous magnesium sulphate. Evaporate the solution resulting from filtration to obtain the crude product. Purify the other product by column chromatography using n-hexane : ethyl acetate (95 : 5 to 70 : 30). |
| Chemical Properties | yellow to khaki-green crystalline powder |
| Uses | 2,5-Dihydroxybenzaldehyde (cas# 1194-98-5) is a compound useful in organic synthesis. |
| Definition | ChEBI: A dihydroxybenzaldehyde carrying hydroxy groups at positions 2 and 5. |
| 2,5-Dihydroxybenzaldehyde Preparation Products And Raw materials |
| Preparation Products | 2,5-DIETHOXYBENZALDEHYDE |
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