Product

4-Hydroxyphenylacetamide

CAS No.：17194-82-0

Other grades of this product :

4-Hydroxyphenylacetamide Basic information

Product Name:	4-Hydroxyphenylacetamide
Synonyms:	4-HYDROXYPHENYLACETAMIDE;4-HYDROXYBENZENEACETAMIDE;2-(4-HYDROXYPHENYL)ACETAMIDE;2-(4-HYDROXYPHENYL)-ETHYLAMIDE;4-HYDROXYPHENYLACETAMIDEATENOLOL;LABOTEST-BB LT00848172;ATENOLOL IMP A;ATENOLOL IMPURITY A
CAS:	17194-82-0
MF:	C8H9NO2
MW:	151.16
EINECS:	241-235-0
Product Categories:	Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;pharmaceutical;Amides;Carbonyl Compounds;Organic Building Blocks
Mol File:	17194-82-0.mol

4-Hydroxyphenylacetamide Chemical Properties

Melting point	176-178 °C (lit.)
Boiling point	273.17°C (rough estimate)
density	1.2023 (rough estimate)
refractive index	1.5810 (estimate)
storage temp.	Inert atmosphere,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Fine Crystalline Powder
pka	9.99±0.26(Predicted)
color	Beige
Water Solubility	soluble
BRN	2085984
InChIKey	YBPAYPRLUDCSEY-UHFFFAOYSA-N
CAS DataBase Reference	17194-82-0(CAS DataBase Reference)
NIST Chemistry Reference	4-Hydroxyphenylacetamide(17194-82-0)
EPA Substance Registry System	Benzeneacetamide, 4-hydroxy- (17194-82-0)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-24/25-37/39
WGK Germany	3
RTECS	AC3851500
Hazard Note	Irritant
TSCA	Yes
HS Code	29242990

MSDS Information

Provider	Language
2-(4-Hydroxyphenyl)acetamide	English
SigmaAldrich	English
ACROS	English
ALFA	English

4-Hydroxyphenylacetamide Usage And Synthesis

Chemical Properties	beige fine crystalline powder
Uses	4-(Hydroxyphenyl)acetamide is used as an intermediate for the synthesis of Atenolol (A790075) and various other organic compounds and pharmaceuticals. It is a process impurity for Atenolol (A790075)
Uses	4-(Hydroxyphenyl)acetamide (Atenolol EP Impurity A) is used as an intermediate for the synthesis of Atenolol (A790075) and various other organic compounds and pharmaceuticals. It is a process impurity for Atenolol (A790075)

4-Hydroxyphenylacetamide Preparation Products And Raw materials

Raw materials

Glyoxal-->4-Chlorobenzyl cyanide-->4-Hydroxyphenylacetic acid-->Ammonium sulfide-->3'-Hydroxyacetophenone-->4-Hydroxybenzyl cyanide-->4-Aminophenylacetonitrile-->Phenol, 4-[2-(bromomethyl)-1,3-dioxolan-2-yl]--->Benzeneacetyl chloride, 4-hydroxy--->2-(4-HYDROXYPHENYL)ACETALDEHYDE-->p-Hydroxyphenyl propanoate-->3,5-Dibromo-L-tyrosine-->Methyl 4-hydroxyphenylacetate-->4-ACETOXYACETOPHENONE-->4'-Hydroxyacetophenone-->3,5-Diiodo-L-tyrosine dihydrate-->Methyl formate

Preparation Products

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE

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