2-(chloromethyl)-4-methylquinazoline

2-(chloromethyl)-4-methylquinazoline
  • CAS No.:109113-72-6
Other grades of this product :
2-(chloromethyl)-4-methylquinazoline Basic information
Product Name:2-(chloromethyl)-4-methylquinazoline
Synonyms:2-(chloromethyl)-4-methylquinazoline;Quinazoline,2-(chloroMethyl)-4-Methyl-;Linagliptin interMediate A;2-chloroMethyl-4-Methyl quinaoline;Linagliptin INT3;Linaint-I;2-(chloromethyl)-4-methylquizoline;Linagliptin 2-Chloromethyl Impurity
CAS:109113-72-6
MF:C10H9ClN2
MW:192.64
EINECS:476-280-7
Product Categories:Intermediates
Mol File:109113-72-6.mol
2-(chloromethyl)-4-methylquinazoline Chemical Properties
Melting point 61.0 to 65.0 °C
Boiling point 240.0±32.0 °C(Predicted)
density 1.251
vapor pressure 0Pa at 20℃
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka1.86±0.50(Predicted)
form powder to crystal
color Light yellow to Yellow to Orange
Water Solubility 3.11g/L at 20℃
λmax318nm(EtOH)(lit.)
InChIKeyUHCUBOJGMLASBY-UHFFFAOYSA-N
LogP1.9 at 25℃
Safety Information
RIDADR 3261
HazardClass 8
PackingGroup III
HS Code 2933998090
MSDS Information
2-(chloromethyl)-4-methylquinazoline Usage And Synthesis
Chemical PropertiesWhite to yellow powder
Synthesis Reference(s)Journal of Heterocyclic Chemistry, 23, p. 1263, 1986 DOI: 10.1002/jhet.5570230458
Flammability and ExplosibilityNotclassified
2-(chloromethyl)-4-methylquinazoline Preparation Products And Raw materials
Raw materialsRo 5-3663-->2-Aminoacetophenone

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