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| Dodecyltriphenylphosphonium bromide Basic information |
| Dodecyltriphenylphosphonium bromide Chemical Properties |
| Melting point | 85-88 °C(lit.) | | storage temp. | RT | | solubility | Soluble in DMSO (50 mg/ml) or ethanol (25 mg/mL) | | form | solid | | color | White | | Sensitive | Hygroscopic | | BRN | 3581921 | | Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. | | CAS DataBase Reference | 15510-55-1(CAS DataBase Reference) |
| Dodecyltriphenylphosphonium bromide Usage And Synthesis |
| Description | Dodecyl-TPP (15510-55-1) is a mitochondria-targeting agent which inhibits mitochondrial function inhibiting oxidative phosphorylation and shifting cell metabolism to glycolysis.1 Potently eradicates cancer stem cells (50 nm to 1 mM) selectively over normal cells1. Synergizes with FDA-approved drugs such as doxycycline and niclosamide as well as natural compounds such as berberine. Selectively inhibits the growth of Gram-positive over Gram-negative bacteria.2 | | Definition | ChEBI: An organic bromide salt that containing equal numbers of dodecyl(triphenyl)phosphonium cations and bromide anions. | | References | References: |
| Dodecyltriphenylphosphonium bromide Preparation Products And Raw materials |
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