DL-Lactide

DL-Lactide
  • CAS No.:95-96-5
Other grades of this product :
DL-Lactide Basic information
Uses
Product Name:DL-Lactide
Synonyms:2,5-dimethyl-3,6-dioxo-1,4-dioxane;2,5-dioxo-3,6-dimethyl-1,4-dioxane;2-hydroxy-propanoicacibimol.cyclicester;3,6-diketo-2,5-dimethyl-1,4-dioxane;3,6-Dimethyl-2,5-dioxo-1,4-dioxane;3,6-dimethyl-p-dioxane-2,5-dione;3,6-dimethyl-p-dioxane-5-dione;D,L-Lactide S
CAS:95-96-5
MF:C6H8O4
MW:144.13
EINECS:202-468-3
Product Categories:Biodegradable Polymer Monomers;Building Blocks;Carbonyl Compounds;Chemical Synthesis;Lactones;Materials Science;Dioxanes;Dioxanes & Dioxolanes;Functional Materials;Lactones & Lactides (for High-Performance Polymer Research);Reagent for High-Performance Polymer Research;Monomers;Organic Building Blocks;Polymer Science;95-96-5
Mol File:95-96-5.mol
DL-Lactide Chemical Properties
Melting point 116-119 °C
Boiling point 142 °C8 mm Hg(lit.)
density 1.186±0.06 g/cm3(Predicted)
vapor pressure 0.311Pa at 25℃
Fp 180°C
storage temp. 2-8°C
solubility Soluble in chloroform and methanol. Slightly soluble in benzene.
form Crystalline Powder
color White
Water Solubility 16.3g/L at 20℃
Sensitive Moisture Sensitive
BRN 82121
LogP0.4 at 25℃
NIST Chemistry Reference1,4-Dioxane-2,5-dione, 3,6-dimethyl-(95-96-5)
EPA Substance Registry System1,4-Dioxane-2,5-dione, 3,6-dimethyl- (95-96-5)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38-36
Safety Statements 26-37/39
WGK Germany 2
RTECS JH1100000
TSCA Yes
HS Code 29322090
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
DL-Lactide Usage And Synthesis
UsesDL-Lactide is used to produce 2-hydroxy-propionic acid 1-(1-phenyl-ethoxycarbonyl)-ethyl ester. It acts as an important raw material and an intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyes. It is involved in enzymatic alcoholysis to produce both alkyl (R)-lactates and alkyl (S,S)-lactyllactates.DL-Lactide is often used as a protective layer in wound coatings, or as anchors, screws or mesh in surgery, since it degrades in about six months to the innocuous lactic acid.
Chemical PropertiesWhite crystalline powder
UsesEnzymatic alcoholysis of this racemic lactide catalyzed by commercial Novozym® 435 produces both alkyl (R)-lactates and alkyl (S,S)-lactyllactates in good yield and high enantiopurity.
UsesDL-Lactide is used to produce 2-hydroxy-propionic acid 1-(1-phenyl-ethoxycarbonyl)-ethyl ester. It acts as an important raw material and an intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyes. It is involved in enzymatic alcoholysis to produce both alkyl (R)-lactates and alkyl (S,S)-lactyllactates.
General Description3,6-Dimethyl-1,4-dioxane-2,5-dione (or rac-lactide), is the 50:50 racemic mixture of D- and L-Lactide. Rac-lactide is a lactone derived from lactic acid that has attracted great interest in academia and commercial applications, as it is derived from abundant renewable resources. Rac-lactide can be ready polymerized via ring-opening polymerization, using a variety of metal or organocatalysts, yielding poly(D,L-lactide). While the resulting polymer is generally amorphous, the use of stereospecific catalysts can lead to heterotactic PLA, which exhibits some degree of crystallinity.
Flammability and ExplosibilityNonflammable
DL-Lactide Preparation Products And Raw materials
Preparation Productspolylactic acid and its copolymer-->Potassium lactate

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