4-(Dimethylamino)benzophenone

4-(Dimethylamino)benzophenone
  • CAS No.:530-44-9

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
4-(Dimethylamino)benzophenone Basic information
Product Name:4-(Dimethylamino)benzophenone
Synonyms:(4-Dimethylamino-phenyl)-phenyl-methanone;[4-(Dimethylamino)phenyl](phenyl)methanone;[4-(dimethylamino)phenyl]phenyl-methanon;[4-(Dimethylamino)phenyl]phenylmethanone;4-Dimethylaminobenzophenon;Benzenamine,N,N-dimethyl-4-(phenylmethanone)-;Benzophenone, 4-(dimethylamino)-;Methanone,[4-(dimethylamino)phenyl]phenyl-
CAS:530-44-9
MF:C15H15NO
MW:225.29
EINECS:208-478-4
Product Categories:Aromatic Benzophenones & Derivatives (substituted);Amine Photochemical CoinitiatorsPolymerization Initiators;Benzophenone;Organic Photoinitiators;Polymer Science;Polymerization Initiators
Mol File:530-44-9.mol
4-(Dimethylamino)benzophenone Chemical Properties
Melting point 88-90 °C(lit.)
Boiling point 250 °C / 15mmHg
density 1.0463 (rough estimate)
refractive index 1.5200 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form powder to crystal
pka2.12±0.12(Predicted)
color White to Light yellow to Green
Water Solubility insoluble
Merck 14,3233
InChIKeyBEUGBYXJXMVRFO-UHFFFAOYSA-N
CAS DataBase Reference530-44-9(CAS DataBase Reference)
NIST Chemistry ReferenceMethanone, [4-(dimethylamino)phenyl]phenyl-(530-44-9)
EPA Substance Registry SystemMethanone, [4-(dimethylamino)phenyl]phenyl- (530-44-9)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39
WGK Germany 3
TSCA Yes
HS Code 29223900
MSDS Information
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4-(Dimethylamino)benzophenone English
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4-(Dimethylamino)benzophenone Usage And Synthesis
Chemical PropertiesYELLOW CRYSTALLINE POWDER OR CRYSTALS
Uses4-(Dimethylamino)benzophenone is an important organic intermediate. It can be used in agrochemical, pharmaceutical and dyestuff field.
Synthesis Reference(s)Synthesis, p. 544, 1986 DOI: 10.1055/s-1986-31696Tetrahedron Letters, 34, p. 7595, 1993 DOI: 10.1016/S0040-4039(00)60409-4
Purification MethodsCrystallise the pale green p-dimethylaminobenzophenone from EtOH. Dissolve 100g in 600mL of boiling EtOH, add 5g of charcoal, cool, isolate the solid by centrifugation and similarly wash the pale crystals with ice-cold EtOH. When filtered by suction, EtOH solution remains on the crystals and turns deep green in air. Dry it in a vacuum and store it in the dark. The hydrazone has m 128-130o and forms a ketyl with potassium. [Hurd & Webb Org Synth Coll Vol I 217 1941, Beilstein 14 H 82, 14 I 288, 14 III 218, 14 IV 248.]
4-(Dimethylamino)benzophenone Preparation Products And Raw materials
Raw materialsPhosphorus oxychloride-->N-Methylaniline-->BENZANILIDE

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