1-METHYLHYDANTOIN

1-METHYLHYDANTOIN
  • CAS No.:616-04-6
Other grades of this product :
1-METHYLHYDANTOIN Basic information
Product Name:1-METHYLHYDANTOIN
Synonyms:1-Methyl-2,4-imidazolidinedione;Dioxy-creatinine;Hydantoin, 1-methyl-;1-Methylhydantoine;1-methylimidazolidine-2,4-dione;N-Methylhydantoin;1-Methylhydantoin 97%;1-Methylhydantoin, 97% 5GR
CAS:616-04-6
MF:C4H6N2O2
MW:114.1
EINECS:210-460-6
Product Categories:Building Blocks;Heterocyclic Building Blocks;Imidazolines/Imidazolidines
Mol File:616-04-6.mol
1-METHYLHYDANTOIN Chemical Properties
Melting point 156-157 °C(lit.)
Boiling point 213.59°C (rough estimate)
density 1.284
refractive index 1.4487 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka8.94±0.10(Predicted)
form Solid
color White to Off-White
Water Solubility Soluble in methanol. (almost transparency). Insoluble in water.
CAS DataBase Reference616-04-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Safety Statements 24/25
WGK Germany 3
Hazard Note Irritant
HS Code 29332100
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
1-METHYLHYDANTOIN Usage And Synthesis
Chemical PropertiesWHITE FINE CRYSTALLINE POWDER
UsesReactant for organocatalytic tandem three component reactions of aldehyde, alkyl vinyl ketone, and amideReactant for synthesis of:
  • Selective angiotensin II AT2 receptor agonists with reduced CYP 450 inhibition
  • Allosteric glucokinase activators
  • Hydantoin derivatives with antiproliferative activity
  • Thiohydantoins
  • P2X7 receptor antagonists
DefinitionChEBI: A imidazolidine-2,4-dione that is the N-methyl-derivative of hydantoin.
Metabolic pathwayThe metabolic pathway of 1-methylhydantoin via 5-hydroxy-1-methylhydantoin, methylparabanic acid, and 5-N-methyloxaluric acid proves to be a major and general metabolic pathway in rabbits.
1-METHYLHYDANTOIN Preparation Products And Raw materials

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