Other grades of this product :
| Boc-N-methyl-L-leucine Basic information |
| Product Name: | Boc-N-methyl-L-leucine | | Synonyms: | N-ALPHA-T-BUTYLOXYCARBONYL-N-ALPHA-METHYL-L-LEUCINE;N-ALPHA-T-BUTOXYCARBONYL-N-ALPHA-METHYL-L-LEUCINE;N-ALPHA-T-BUTOXYCARBONYL-BETA-T-BUTYL-L-ALANINE;N-ALPHA-T-BUTOXYCARBONYL-GAMMA-METHYL-L-LEUCINE;N-ALPHA-TERT-BUTYLOXYCARBONYL-N-ALPHA-METHYL-L-LEUCINE;N-ALPHA-T-BOC-N-ALPHA-METHYL-L-LEUCINE;BOC-BETA-TBU-ALANINE;BOC-BETA-TBU-ALA-OH | | CAS: | 53363-89-6 | | MF: | C12H23NO4 | | MW: | 245.32 | | EINECS: | | Product Categories: | amino acids;Amino Acid Derivatives;N-Methyl Amino Acids | | Mol File: | 53363-89-6.mol |
| Boc-N-methyl-L-leucine Chemical Properties |
| Melting point | 55-60 °C | | Boiling point | 338.2±21.0 °C(Predicted) | | density | 1.053±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,2-8°C | | pka | 4.04±0.21(Predicted) | | optical activity | [α]20/D 36±2°, c = 1% in methylene chloride | | BRN | 2373250 | | InChIKey | YXJFAOXATCRIKU-VIFPVBQESA-N | | CAS DataBase Reference | 53363-89-6(CAS DataBase Reference) |
| WGK Germany | 3 | | HS Code | 2924 19 00 | | HazardClass | IRRITANT |
| Boc-N-methyl-L-leucine Usage And Synthesis |
| Description | Boc-N-methyl-L-leucine is the BOC (tert-butyloxycarbonyl) protected N-methylated leucine. The N-methylated amino acid is quite useful in the peptide synthesis, giving a lot of improved properties to peptide. Studies have shown that peptide containing N-methylated amino acids obtain increased proteolytic stability, increased membrane permeability, and altered conformation. The effects of N-methylated amino acids are quite important in the development of therapeutic peptide compound as well as in the assay of biological activity of some modified peptides. BOC group can be easily removed by treatment with strong acids such as trifluoroacetic acid.
| | Uses | Boc-N-methyl-L-leucine, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance. | | References | https://en.wikipedia.org/wiki/Tert-Butyloxycarbonyl_protecting_group
http://pubs.acs.org/doi/abs/10.1021/cr030024z?src=recsys&journalCode=chreay
|
| Boc-N-methyl-L-leucine Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye