Product

1H-IMidazole-5-carboxylic acid, 4-(1-hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1-(triphenylMethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]Methyl]-, ethyl ester

CAS No.：144690-33-5

Other grades of this product :

1H-IMidazole-5-carboxylic acid, 4-(1-hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1-(triphenylMethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]Methyl]-, ethyl ester Basic information

Product Name:	1H-IMidazole-5-carboxylic acid, 4-(1-hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1-(triphenylMethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]Methyl]-, ethyl ester
Synonyms:	1H-IMidazole-5-carboxylic acid, 4-(1-hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1-(triphenylMethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]Methyl]-, ethyl ester;Trityl olMesartan ethyl ester;OlMesartan Ethyl Ester Trityl IMpurity;4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid ethyl ester;1H-IMidazole-5-carboxylic acid, 4-(1-hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1;Ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylate;OMSTINT-J;Olmesartan Medoxomil-19
CAS:	144690-33-5
MF:	C45H44N6O3
MW:	716.87
EINECS:	604-436-8
Product Categories:
Mol File:	144690-33-5.mol

1H-IMidazole-5-carboxylic acid, 4-(1-hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1-(triphenylMethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]Methyl]-, ethyl ester Chemical Properties

Melting point	161℃
Boiling point	889.7±75.0 °C(Predicted)
density	1.18±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	13.18±0.29(Predicted)
color	White to Off-White
Water Solubility	4.6μg/L at 25℃
LogP	9.64 at 25℃

Safety Information

MSDS Information

1H-IMidazole-5-carboxylic acid, 4-(1-hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1-(triphenylMethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]Methyl]-, ethyl ester Usage And Synthesis

Uses	Tritylolmesartan Ethyl Ester is an impurity of olmesartan medoxomil (O550000), an angiotensin II receptor antagonist and anti-hypertensive drug.

1H-IMidazole-5-carboxylic acid, 4-(1-hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1-(triphenylMethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]Methyl]-, ethyl ester Preparation Products And Raw materials

Raw materials

1H-Tetrazole, 5-(4'-methyl[1,1'-biphenyl]-2-yl)-1-(phenylmethyl)--->1-benzyl-5-phenyltetrazole-->5-[4’-Hydroxymethyl-(1,1’-biphenyl)-2-yl]-1-triphenylmethyltetrazole-->OlMesartan Ethyl Ester IMpurity-->[2'-(Triphenylmethyltetrazol-5-yl)biphenyl-4-yl]carboxaldehyde-->Trityl olMesartan acid-->N-BENZYLBENZAMIDE-->Ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-imidazole-5-carboxylate-->5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole-->Triphenylmethyl Chloride-->4-Bromotoluene-->Benzoyl chloride

Preparation Products

Trityl olmesartan

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