HISTONE TYPE VIII-S

CAS No.：9064-47-5

Other grades of this product :

HISTONE TYPE VIII-S Basic information

Product Name:	HISTONE TYPE VIII-S
Synonyms:	histone type iii-S from calf thymus;histone type iii-ss from calf thymus;histone type viii-S from calf thymus;Histones nucleo froM calf thyMus;Histones,dried(Calf thyMus);Histone III (calfthyMus) (9CI);f3histonefraction;histoneiii(calfthymus)
CAS:	9064-47-5
MF:	NULL
MW:	0
EINECS:	297-235-6
Product Categories:	Protein Kinase C (PKC)Peptides for Cell Biology;Protein Kinase Related Peptides;Biochemicals and Reagents;Protein Kinase Substrates;Serine/Threonine Kinase Biology;Serine/Threonine Kinase Substrates;Bovine;Proteins and Derivatives
Mol File:	Mol File

HISTONE TYPE VIII-S Chemical Properties

storage temp.	2-8°C
solubility	H2O: soluble10mg/mL, clear to hazy, colorless to light yellow
form	lyophilized powder
BRN	1895465

Safety Information

WGK Germany	3
RTECS	MS3450700
F	10-21
Toxicity	LD50 intravenous in rat: 45mg/kg

MSDS Information

HISTONE TYPE VIII-S Usage And Synthesis

Uses	Histone is suitable for use: as a positive control in the in vitro kinase assay to examine the ability of Cdc2-cyclin B1 to phosphorylate GST-CD-4 protein in Cdk5 activity assay in histone H1 kinase assay as a Poly(ADP-ribose) (PAR) acceptor in the assessment of in vitro PAR polymerase activity as an acceptor of ³²P from [γ-³²P]ATP in order to measure protein kinase activity of lysate from small and large luteal cells
General Description	Histones are octameric proteins containing H3, H4, H2A and H2B. It is the core protein around which DNA is wound forming the nucleosome structure. The core histone proteins contain globular domains. Each protein is composed of basic amino acids at its N-terminal. The H2A has an extra amino acid at its C-terminal end forming a histone tail. The nucleosome structure is stabilized by the linker histones during chromatin condensation.
Biochem/physiol Actions	Histones are a group of proteins characterized by high levels of lysine and arginine that form reversible complexes with DNA. Based on the fractions, the molar mass of histones varies between 11-21kDa. Five different fractions have been isolated and characterized. They include H1 (lysine rich), H2a and H2b that are slightly lysine rich, H3 and H4 that are arginine rich. H1 acts as a link between "beads" (nu bodies) on the chromatin chain.

HISTONE TYPE VIII-S Preparation Products And Raw materials

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