Other grades of this product :
| Tubacin Basic information |
| Product Name: | Tubacin | | Synonyms: | Tubacin;N1-(4-((2R,4R,6S)-4-((4,5-diphenyloxazol-2-ylthio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-dioxan-2-yl)phenyl)-N8-hydroxyoctanediamide;N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-octanediamide Tubacin;N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-octanediamide;Tubacin, >=98%;BML-GR362;N1-(4-((2R,4R,6S)-4-(((4,5-Diphenyloxazol-2-yl)thio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-di;Tubacin (BML-GR362) | | CAS: | 537049-40-4 | | MF: | C41H43N3O7S | | MW: | 721.86 | | EINECS: | | Product Categories: | Inhibitors | | Mol File: | 537049-40-4.mol |
| Tubacin Chemical Properties |
| Melting point | 155 - 157°C | | storage temp. | -20°C | | solubility | DMSO: ≥10mg/mL | | form | powder | | color | white to tan |
| Tubacin Usage And Synthesis |
| Uses | Tubacin is tubulin acetylation inducer that selectively inhibits histone deacetylase (HDAC6). | | Biochem/physiol Actions | Tubacin triggers the release of reactive oxygen species and mediates caspase-3-independent apoptosis of Epstein-Barr virus (EBV)-positive Burkitt lymphoma cells. It suppresses the proliferation of acute lymphoblastic leukemia (ALL) cells and enhances the effect of chemotherapy to treat ALL cells. Tubacin prevents the epileptic activity and neuronal migration defects caused due to lowered expression of Srpx2 in rats. |
| Tubacin Preparation Products And Raw materials |
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