Product

1-Boc-4-(aminomethyl)piperidine

CAS No.：144222-22-0

Other grades of this product :

1-Boc-4-(aminomethyl)piperidine Basic information

Product Name:	1-Boc-4-(aminomethyl)piperidine
Synonyms:	1-Boc-4-(aminomethyl)piperidine, 1-Boc-4-piperidylmethylamine;4-(aminometh;t-Butyl 4-(aminomethyl)piperidine-1-carboxylate;1-Boc-4-(aminomethyl)piperidine ,97%;4-(Aminomethyl)piperidine, N1-BOC protected 97%;1-Boc-4-aminomethylpiperi...;4-(Aminomethyl)-1-(tert-butoxycarbonyl)piperidine, tert-Butyl 4-(aminomethyl)piperidine-1-carboxylate;1,1-DiMethylethyl 4-(aMinoMethyl)-1-piperidinecarboxylate
CAS:	144222-22-0
MF:	C11H22N2O2
MW:	214.3
EINECS:
Product Categories:	Heterocyclic Compounds;Building Blocks;pharmacetical;Piperidine;Heterocyclic Building Blocks;Piperidines
Mol File:	144222-22-0.mol

1-Boc-4-(aminomethyl)piperidine Chemical Properties

Boiling point	237-238 °C(lit.)
density	1.013 g/mL at 25 °C(lit.)
refractive index	n20/D1.473(lit.)
Fp	>230 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Soluble in chloroform and methanol.
form	Liquid or Low Melting Solid
pka	10.13±0.29(Predicted)
color	Colorless to yellow
CAS DataBase Reference	144222-22-0(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,C,N
Risk Statements	36/37/38-34-50
Safety Statements	26-36-45-36/37/39-24/25-23-61
RIDADR	UN 3082 9 / PGIII
WGK Germany	3
F	10-34
HazardClass	IRRITANT
HS Code	29339900

MSDS Information

Provider	Language
SigmaAldrich	English

1-Boc-4-(aminomethyl)piperidine Usage And Synthesis

Chemical Properties	White Low Melting Solid
Uses	1-Boc-4-(aminomethyl)piperidine is a protected 4-substituted piperidinecarboxylate used in the preparation of orally active platelet-activating factor antagonists as well as other biologically active compounds.
Uses	4-Aminomethyl-1-Boc-piperidine is used in the preparation biologically active compounds and orally active platelet-activating factor antagonists. It is used as an inhibitor for aspartic acid protease and Kinesin spindle protein. It is an active reactant involved in the enantioselective synthesis of N-alkyl terminal aziridines.

1-Boc-4-(aminomethyl)piperidine Preparation Products And Raw materials

Raw materials

Ethanol-->Sodium hydroxide-->Ethyl acetate-->Methanol-->Tetrahydrofuran-->Dichloromethane-->PETROLEUM ETHER-->Sodium carbonate-->Triethylamine-->Lithium Aluminum Hydride-->1,4-Dioxane-->Di-tert-butyl dicarbonate-->Benzaldehyde-->Tosyl chloride-->Sodium amide-->1,1'-Carbonyldiimidazole-->Isonipecotic acid-->4-Methylmorpholine-->Sodium bisulfate-->4-Piperidinemethanol

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