(S)-(-)-1-BENZYL-2-PYRROLIDINEMETHANOL

CAS No.：53912-80-4

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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(S)-(-)-1-BENZYL-2-PYRROLIDINEMETHANOL Basic information

Product Name:	(S)-(-)-1-BENZYL-2-PYRROLIDINEMETHANOL
Synonyms:	(1-Benzyl-2-pyrrolidinyl)methanol;[1-(phenylmethyl)-2-pyrrolidinyl]methanol;[1-(phenylmethyl)pyrrolidin-2-yl]methanol;1-N-Benzyl-L-prolinol;(S)-1-(Phenylmethyl)-2-pyrrolidinemethanol;N-BENZYL-L-PROLINOL;(S)-(1-BENZYL-PYRROLIDIN-2-YL)-METHANOL;S(-)-1-BENZYLPYRROLIDINE-2-METHANOL
CAS:	53912-80-4
MF:	C12H17NO
MW:	191.27
EINECS:
Product Categories:
Mol File:	53912-80-4.mol

(S)-(-)-1-BENZYL-2-PYRROLIDINEMETHANOL Chemical Properties

Boiling point	115-120 °C/0.5 mmHg (lit.)
density	1.08 g/mL at 25 °C (lit.)
refractive index	n20/D 1.541(lit.)
Fp	>230 °F
storage temp.	Inert atmosphere,2-8°C
pka	14.77±0.10(Predicted)
optical activity	[α]20/D 72.7°, neat
BRN	3663640
InChIKey	ZAIQBJPTOXDDKA-UHFFFAOYSA-N

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
F	3-10-34
HazardClass	IRRITANT
HS Code	2933998090

MSDS Information

Provider	Language
SigmaAldrich	English

(S)-(-)-1-BENZYL-2-PYRROLIDINEMETHANOL Usage And Synthesis

Chemical Properties	Colorless to pale yellow liquid
Uses	Precursor in the synthesis of proline-derived homochiral amine oxides. Starting material for enantiomerically pure 3-hydroxypiperidine, a structural feature present in many natural products.

(S)-(-)-1-BENZYL-2-PYRROLIDINEMETHANOL Preparation Products And Raw materials

Preparation Products

(S)-3-Amino-1-N-Boc-piperidine

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