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| TABERSONINE Basic information |
| Product Name: | TABERSONINE | | Synonyms: | ,12-beta,19-alpha)-;aspidospermidine-3-carboxylicacid,2,3,6,7-tetrahydro-,methylester,(5-alpha;tabersonin;TABERSONINE;Aspidospermidine-3-carboxylic acid, 2,3,6,7-tetradehydro-, methyl ester, (5alpha,12beta,19alpha)-;TABERSONINE HYDROCHLORIDE FROM VOCANGA AFRICANA 98%;C09244;TABERSONINE(SH) | | CAS: | 4429-63-4 | | MF: | C21H24N2O2 | | MW: | 336.44 | | EINECS: | 224-615-0 | | Product Categories: | Herb extract;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 4429-63-4.mol |
| TABERSONINE Chemical Properties |
| Melting point | 196 °C | | Boiling point | 488.7±45.0 °C(Predicted) | | density | 1.27±0.1 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | solubility | Chloroform (Slightly), Ethanol (Slightly, Sonicated), Ethyl Acetate (Slightly) | | form | Solid | | pka | 7?+-.0.60(Predicted) | | color | Light Yellow to Dark Yellow | | Stability: | Light Sensitive |
| TABERSONINE Usage And Synthesis |
| Description | This alkaloid, found in Amsonia tabernaemontana, is difficult to obtain crystalline
but the hydrochloride is readily crystallizable and has m.p. 195-6°C; [α]D -
310° (c 0.134, MeOH). | | Chemical Properties | Dark Yellow Low Melting Solid | | Occurrence | The seeds of Amsonia elliptica contain this N-oxide at tabersonine. | | Uses | (-)-Tabersonine is one of the terpenoid indole alkaloids (TIAs) from Catharanthus roseus. (-)-Tabersonine shows hypotensive activity, anti-tumor activity, hypoglycemic, diuretic activity. | | Definition | ChEBI: A monoterpenoid indole alkaloid with cytotoxic activity. | | References | lanot, Paourrat, LeMen., Bull. Soc. Chim. Fr., 707 (1954)
Plat et al., Tetrahedron Lett., 271 (1962) |
| TABERSONINE Preparation Products And Raw materials |
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