tert-Butyl 3-aminopyrrolidine-1-carboxylate

CAS No.：186550-13-0

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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tert-Butyl 3-aminopyrrolidine-1-carboxylate Basic information

Product Name:	tert-Butyl 3-aminopyrrolidine-1-carboxylate
Synonyms:	TERT-BUTYL 3-AMINOPYRROLIDINE-1-CARBOXYLATE;1-BOC-3-AMINOPYRROLIDINE;1-N-BOC-3-AMINO-PYRROLIDINE;(+/-)-3-AMINO-1-BOC-PYRROLIDINE;3-AMINO-1-BOC-PYRROLIDINE;(+/-)-3-AMINO-1-N-BOC-PYRROLIDINE;3-AMINO-1-N-BOC-PYRROLIDINE;3-AMINOPYRROLIDINE, N1-BOC PROTECTED
CAS:	186550-13-0
MF:	C9H18N2O2
MW:	186.25
EINECS:	624-257-9
Product Categories:	pharmacetical;Amines;Pyrrolidines;Pyrrole&Pyrrolidine&Pyrroline
Mol File:	186550-13-0.mol

tert-Butyl 3-aminopyrrolidine-1-carboxylate Chemical Properties

Boiling point	257.4±33.0 °C(Predicted)
density	1.022
Fp	91°C
refractive index	1.4710
storage temp.	2-8°C
form	powder to lump to clear liquid
pka	9.55±0.20(Predicted)
color	White or Colorless to Light yellow
Sensitive	Air Sensitive
CAS DataBase Reference	186550-13-0(CAS DataBase Reference)

Safety Information

Hazard Codes	C,Xi,Xn
Risk Statements	36/37/38-44-41-22
Safety Statements	26-36/37/39
RIDADR	2810
WGK Germany	3
Hazard Note	Irritant
HazardClass	8
PackingGroup	Ⅲ
HS Code	29339900

MSDS Information

tert-Butyl 3-aminopyrrolidine-1-carboxylate Usage And Synthesis

Chemical Properties

Colorless low melting solid or liquid

tert-Butyl 3-aminopyrrolidine-1-carboxylate Preparation Products And Raw materials

Raw materials

Ethanol-->Sodium hydroxide-->Methanol-->Tetrahydrofuran-->Dichloromethane-->Sodium-->Triethylamine-->Ammonia-->Isopropyl alcohol-->Di-tert-butyl dicarbonate-->1-Butanol-->Tosyl chloride-->1-(tert-Butoxycarbonyl)-3-pyrrolidinol-->3-Aminopyrrolidine dihydrochloride-->tert-butyl 3-(benzylamino)pyrrolidine-1-carboxylate-->Methyl 1-Boc-3-pyrrolidinecarboxylate-->N-Boc-3-azido-pyrrolidine-->1-BOC-3-METHANESULFONYLOXYPYRROLIDINE

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