| 2-Chloro-4-cyanopyridine Basic information |
| Product Name: | 2-Chloro-4-cyanopyridine |
| Synonyms: | BUTTPARK 43\57-01;4-CYANO-2-CHLORO PYRIDINE;2-CHLORO-4-CYANOPYRIDINE;2-CHLORO-4-PYRIDINECARBONITRILE;2-CHLOROPYRIDINE-4-CARBONITRILE;2-CHLOROISONICOTINONITRILE;2-CHLORO-4-CYANOPYRIDINE 99+%;2-CHLORO-4-CYANOPYRIDINE 2-CHLORO-ISONICOTINONITRILE |
| CAS: | 33252-30-1 |
| MF: | C6H3ClN2 |
| MW: | 138.55 |
| EINECS: | 608-852-0 |
| Product Categories: | Pyridines, Pyrimidines, Purines and Pteredines;Halides;blocks;Pyridine;Chloropyridines;Halopyridines;Carboxes;Pyridines;Boron, Nitrile, Thio,& TM-Cpds;Heterocycles;bc0001 |
| Mol File: | 33252-30-1.mol |
| 2-Chloro-4-cyanopyridine Chemical Properties |
| Melting point | 69-73 °C(lit.) |
| Boiling point | 104-106°C 15mm |
| density | 1.33±0.1 g/cm3(Predicted) |
| Fp | 104-106°C/15mm |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| pka | -1.60±0.10(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| BRN | 113927 |
| InChIKey | QRXBTPFMCTXCRD-UHFFFAOYSA-N |
| CAS DataBase Reference | 33252-30-1(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-20/21/22 |
| Safety Statements | 26-36-36/37/39-36/37 |
| RIDADR | 3276 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29333990 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| ALFA | English |
| 2-Chloro-4-cyanopyridine Usage And Synthesis |
| Chemical Properties | White to off-white solid |
| Uses | 2-Chloro-4-cyanopyridine is an intermediate used to prepare pyrrolopyridine inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2). It is also used to synthesize pyridinyl-tetrazoles as scaffold to identify matrix MMP-13 inhibitors for treatment of osteoarthritis. |
| 2-Chloro-4-cyanopyridine Preparation Products And Raw materials |
| Raw materials | 2-Chloro-4-nitropyridine 1-oxide |
| Preparation Products | 1-(2-CHLORO-PYRIDIN-4-YL)-ETHANONE-->2-Methoxy-4-pyridinecarboxylic acid-->2-PHENYL-ISONICOTINIC ACID-->4-CYANO-2-METHOXYPYRIDINE-->RG120 |
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