Cefmenoxime hydrochloride

Cefmenoxime hydrochloride
  • CAS No.:75738-58-8
Other grades of this product :
Cefmenoxime hydrochloride Basic information
Product Name:Cefmenoxime hydrochloride
Synonyms:8-[2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino-4-[(1-methyltetrazol-5-yl)sulfanylmethyl]-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylic acid hydrochloride (2:1);7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hemihydrochloride;7beta-[2-(2-Aminothiazol-4-yl)-(Z)-2-(methoxyiminoacetamido)]-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]ceph-3-em-4-carboxylic acid hemihydrochloride;Bestcall;Bestron;Cemix;SCE-1365(free acid);Tacef
CAS:75738-58-8
MF:C32H35ClN18O10S6
MW:1059.58
EINECS:278-299-4
Product Categories:CEFMAX;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
Mol File:75738-58-8.mol
Cefmenoxime hydrochloride Chemical Properties
Melting point >175°C (dec.)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMSO (Slightly, Heated), Methanol (Slightly)
form Solid
color Off-White to Pale Yellow
Safety Information
HS Code 2941906000
MSDS Information
Cefmenoxime hydrochloride Usage And Synthesis
DescriptionCef menoxime hydrochloride is a third generation cephalosporin antibiotic. Structurally, it possesses the (1-methyl-lH-tetrazol-5-yl)thiomethyl moiety in the 3-position; like several other compounds containing this structural element (moxalactam, cefoperazone, cefamandol), bleeding linked to vitamin K interaction has been reported. Cefmenoxime has activity similar to cefotiuime, ceftizoxime and moxalactam against E.coli, C. diversus, Klebsiella, P. Mirabilis, Salmonella, Shigella, Neiseria spp., S. pyogenes, S. Pneumoniae, and g. influenzae. It is relatively ineffective against Pseudomonas and Bacteroidea.
OriginatorTakeda (Japan)
UsesA third generation cephalosporin antibiotic with strong antimicrobial activities against Streptococcus pneumoniae, Haemophilus influenzae and Moraxella subgenus Branhamella catarrhalis that were 3 major aerobic bacteria from sinusitis.
Usesantibacterial
DefinitionChEBI: The hemihydrochloride salt of cefmenoxime.
Brand nameCefmax (TAP);TACEF;BESTCALL.
Cefmenoxime hydrochloride Preparation Products And Raw materials

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