Product

(R)-4-Benzyl-2-oxazolidinone

CAS No.：102029-44-7

Other grades of this product :

(R)-4-Benzyl-2-oxazolidinone Basic information

Product Name:	(R)-4-Benzyl-2-oxazolidinone
Synonyms:	4-benzyl-2-0xazolidinone;(R)-4-BENZYL-2-OXAZOLIDINONE HPLC 99+%;(R)-4-BENZYL-2-OXAZOLIDINONE 98.0%;(4R)-4-(Phenylmethyl)-1,3-oxazolidin-2-one;(4R)-4-(Phenylmethyl)-2-oxazolidinone;(4R)-Benzyloxazolidin-2-one;(4R)-Phenylmethyl-2-oxazolidinone;(R)-(+)-4-BENZYL-2-OXAZOLIDINONE FOR SYN
CAS:	102029-44-7
MF:	C10H11NO2
MW:	177.2
EINECS:	600-264-2
Product Categories:	Asymmetric Synthesis;Chiral Auxiliaries;Peptide;Aromatics;Chiral Reagents;Heterocycles;Chiral Compounds;chiral;Asymmetric Synthesis;Chiral Building Blocks;Glycidyl Compounds, etc. (Chiral);Synthetic Organic Chemistry;Chiral chemicals;Ketone;Oxazolidinone;Oxazolidinone Derivatives
Mol File:	102029-44-7.mol

(R)-4-Benzyl-2-oxazolidinone Chemical Properties

Melting point	88-90 °C
alpha	62 º (C=1, CHCl3)
Boiling point	309.12°C (rough estimate)
density	1.1607 (rough estimate)
refractive index	14.5 ° (C=5, MeOH)
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform (Slightly)
pka	12.78±0.40(Predicted)
form	Crystalline Powder
color	White to almost white
optical activity	[α]18/D +64°, c = 1 in chloroform
Water Solubility	Insoluble in water. Soluble in Chloroform.
Sensitive	Hygroscopic
BRN	4782551
CAS DataBase Reference	102029-44-7(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	22-24/25-36-26
WGK Germany	3
F	3-10
HS Code	29349990

MSDS Information

Provider	Language
ACROS	English
SigmaAldrich	English
ALFA	English

(R)-4-Benzyl-2-oxazolidinone Usage And Synthesis

Description	(R)-4-Benzyl-2-oxazolidinone is a derivative of oxazolidinone. It can be used in the preparation of enantiopure carbocyclic nucleosides, which act as a HIV protease inhibitor. It can also be used as a chiral auxiliary in the enantioselective synthesis of (2R, 2′S)-erythro-methylphenidate, beta-lactams and alpha-amino acids. Its end product includes asymmetric single isomeric drugs such as antitumor, anesthetic and entipasmodic products.
Chemical Properties	white to light yellow crystal powde
Uses	An oxazolidinone used in chiral auxiliary asymetric synthesis
Uses	intermediate for Aliskiren hemifumarate, Darifenacin HBr, Zolmitriptan
Uses	(R)-(+)-4-Benzyl-2-oxazolidinones are used in the enantioselective synthesis of beta-lactams and alpha-amino acids. End products can include asysmmetric single isomeric drugs of antitumor, anesthetic, antipasmodic products. Used in the synthesis of HIV protease inhibitors. An oxazolidinone used in chiral auxiliary asymetric synthesis.
References	http://www.sigmaaldrich.com/catalog/product/aldrich/300977? lang=en®ion=US https://www.alfa.com/en/catalog/A16770/ Shieh, Wen Chung, et al. "Synthesis of enantiomerically enriched 4- piperidinylglycine." US, US 6670477B2. 2003.

(R)-4-Benzyl-2-oxazolidinone Preparation Products And Raw materials

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