Other grades of this product :
| Tiotropium bromide hydrate Basic information |
| Product Name: | Tiotropium bromide hydrate | | Synonyms: | (1R,2R,4S,5S,7S)-7-[2-HYDROXY-2,2-DI(2-THIENYL)ACETOXY]-9,9-DIMETHYL-3-OXA-9-AZONIATRICYCLO[3.3.1.02,4] NONANE BROMIDE MONOHYDRATE;tiotropium bromide hydrate;TIOTROPIUM BROMIDE MONOHYDRATE;TIOTROPIUM BROMDIE;Tiotropium;(1a,2b,4b,5a,7b)-7-[(hydroxydi-2-thienylacety l)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane bromide hydrate;(1a,2b,4b,5a,7b)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane bromide;TiotropiuM BroMide MonohydrateTiotropiuM BroMide Monohydrate | | CAS: | 139404-48-1 | | MF: | C19H22BrNO4S2.H2O | | MW: | 490.43 | | EINECS: | 690-508-4 | | Product Categories: | API;Inhibitors | | Mol File: | 139404-48-1.mol |
| Tiotropium bromide hydrate Chemical Properties |
| solubility | Sparingly soluble in water, soluble in methanol, practically insoluble in methylene chloride. | | InChIKey | MQLXPRBEAHBZTK-SEINRUQRSA-M | | CAS DataBase Reference | 139404-48-1(CAS DataBase Reference) |
| Tiotropium bromide hydrate Usage And Synthesis |
| Chemical Properties | White or yellowish-white powder or crystals. | | Uses | Tiotropium Bromide hydrate is a hydrate of tiotropium bromide (Spiriva; Tiova; BA 679BR; tiopropium) that is an anticholinergic and bronchodilator and a muscarinic receptor antagonist. Although tiotropium Bromide (Spiriva; Tiova; BA 679BR; tiopropium) doe | | Clinical Use | Maintenance treatment of chronic obstructive pulmonary disease | | Drug interactions | Potentially hazardous interactions with other drugs
Avoid administration with other anti-cholinergic
drugs.
Anti-arrhythmics: increased risk of antimuscarinic
side effects with disopyramide. | | Metabolism | Tiotropium is excreted largely unchanged in the urine, although it may undergo some metabolism by non-enzymatic cleavage and by the cytochrome P450 isoenzymes CYP2D6 and CYP3A4. |
| Tiotropium bromide hydrate Preparation Products And Raw materials |
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