2-bromo-4-methylpropiophenone

CAS No.：1451-82-7

Other grades of this product :

2-bromo-4-methylpropiophenone Basic information

Description Uses Reference

Product Name:	2-bromo-4-methylpropiophenone
Synonyms:	4-Methylphenyl 1-BroMoethyl Ketone;2-bromo-4-methylpropiophenone;2-bromo-1-(4-methylphenyl)propan-1-one;2-Bromo-1-(4-methylphenyl)-1-propanone;1-Propanone,2-broMo-1-(4-Methylphenyl)-;2-BROMO-4'-METHYLPROPIOPHENE;2-Bromo-1-(p-tolyl);Quality guarantee EG-2201 power
CAS:	1451-82-7
MF:	C10H11BrO
MW:	227.1
EINECS:	696-162-0
Product Categories:	Medical research;Aromatics;Intermediates;Miscellaneous Reagents;organic interme;Intermediate;1451-82-7
Mol File:	1451-82-7.mol

2-bromo-4-methylpropiophenone Chemical Properties

Melting point	75-77℃
Boiling point	273℃
density	1.357
Fp	59℃
storage temp.	Refrigerator
solubility	Soluble in chloroform and methanol.
form	Solid
color	White to Off-White
InChIKey	OZLUPIIIHOOPNQ-UHFFFAOYSA-N

Safety Information

Hazard Codes	Xn
Risk Statements	22

MSDS Information

2-bromo-4-methylpropiophenone Usage And Synthesis

Description	It is usually used as the intermediate and raw material in the fine chemistry industry. Specifically, this chemical can act as the intermediate in the synthesis of 4-methyl methcathinone HCl, which is used as the sample for development and validation of a presumptive colour spot test method for the detection of piperazine analogues in seized illicit materials.¹ Moreover, this compound may function as an effective ingredient to prepare the therapeutically useful 1-phenyl-2-piperidinoalkanol derivatives.² In addition, this substance has been demonstrated to be involved in the preparation of a pharmaceutical composition comprising a pyrrole derivative, which shows a desirable activity for the treatment pollakiuria or urinary incontinence.³
Uses	2-Bromo-4'-methylpropiophenone (cas# 1451-82-7) is a compound useful in organic synthesis.
Reference	Philp, M.; Shimmon, R.; Stojanovska, N.; Tahtouh, M.; Fu, S. L., Development and validation of a presumptive colour spot test method for the detection of piperazine analogues in seized illicit materials. Anal. Methods 2013, 5, 5402-5410. Alexander Wick; Jonathan Frost; Bernard Gaudilliere; Jean Bertin; Regis Dupont; Rousseau, J., Therapeutically useful 1-phenyl-2-piperidinoalkanol derivatives. US Patent 4690931 1987. Masami Tsuda; Mitsushi Tanaka; Nakamura, A., Pyrrole derivatives and medicinal composition. US Patent 5998459 1999.
Chemical Properties	Off-White Solid
Uses	It employed as an important intermediate for raw material for organic synthesis, agrochemical, pharmaceutical and dyestuff field. Also used as intermediate for 4-methylmethcathinone.

2-bromo-4-methylpropiophenone Preparation Products And Raw materials

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