Product

5-AMINO-2-CHLOROPYRIDINE-4-CARBOXYLIC ACID

CAS No.：58483-95-7

Other grades of this product :

5-AMINO-2-CHLOROPYRIDINE-4-CARBOXYLIC ACID Basic information

Product Name:	5-AMINO-2-CHLOROPYRIDINE-4-CARBOXYLIC ACID
Synonyms:	5-AMINO-2-CHLOROPYRIDINE-4-CARBOXYLIC ACID;5-amino-2-chloroisonicotinic acid;5-Amino-2-chloropyridine-4-carboxylic acid ,97%;3-amino-6-chloroisonicotinicacid;5-Amino-2-chloro-4-pyridinecarboxylic acid;5-Amino-2-chloropyridine-4-carboxylic acid, 5-Amino-4-carboxy-2-chloropyridine;5-Amino-2-Chloroisonicotinic Acid(WXC01548);5-Amino-2-chloroisonicotinic
CAS:	58483-95-7
MF:	C6H5ClN2O2
MW:	172.57
EINECS:	687-937-4
Product Categories:	Heterocycle-Pyridine series;Pyridine;Carboxylic Acids;Pyridines;Carboxylic Acids
Mol File:	58483-95-7.mol

5-AMINO-2-CHLOROPYRIDINE-4-CARBOXYLIC ACID Chemical Properties

Boiling point	514.4±50.0 °C(Predicted)
density	1.577±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	3.74±0.10(Predicted)

Safety Information

Risk Statements	36/37/38
Safety Statements	22-26-36/37/39
HazardClass	IRRITANT
HS Code	29339900

MSDS Information

5-AMINO-2-CHLOROPYRIDINE-4-CARBOXYLIC ACID Usage And Synthesis

Chemical Properties	Brown powder
Uses	3-Amino-6-chloroisonicotinic Acid is a useful synthetic intermediate. It can be used to prepare inhibitors of the EGFr and c-erbB-2. It can also be used to synthesise modulators of GHSr-1a for the treatment of type II diabetes and obesity.

5-AMINO-2-CHLOROPYRIDINE-4-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Hydrochloric acid-->Diethyl ether-->Dichloromethane-->Triethylamine-->Ammonium hydroxide-->n-Butyllithium-->Hexane-->1,4-Dioxane-->Di-tert-butyl dicarbonate-->CARBON DIOXIDE-->Trifluoroacetic acid-->N,N,N',N'-Tetramethylethylenediamine-->5-Amino-2-chloropyridine-->5-[(TERT-BUTOXYCARBONYL)AMINO]-2-CHLOROISONICOTINIC ACID-->5-[N-(TERT-BUTOXYCARBONYL)AMINO]-2-CHLOROPYRIDINE-->2-Amino-5-chloropyridine-->6-Chloronicotinic acid

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