5,6-Diamino-1,3-dimethyluracil hydrate

5,6-Diamino-1,3-dimethyluracil hydrate
  • CAS No.:5440-00-6
Other grades of this product :
5,6-Diamino-1,3-dimethyluracil hydrate Basic information
Product Name:5,6-Diamino-1,3-dimethyluracil hydrate
Synonyms:2,4(1H,3H)-Pyrimidinedione, 5,6-diamino-1,3-dimethyl-;5,6-DiaMino-1,3-diMethyluracil hydrate technical grade;5,6-Diamino-1,3-dimethylurea;2,4(1H,3H);5,6-DIAMINO-1,3-DIMETHYLURACIL HYDRATE;3h)-pyrimidinedione,5,6-diamino-1,3-dimethyl-4(1h;5,6-Diamino-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione;Uracil, 5,6-diamino-1,3-dimethyl-
CAS:5440-00-6
MF:C6H10N4O2
MW:170.17
EINECS:226-621-9
Product Categories:Nucleotides and Nucleosides;5-FOA;Bases & Related Reagents;Nucleotides;Building Blocks;C6 to C8;Chemical Synthesis;Heterocyclic Building Blocks;Pyrimidines
Mol File:5440-00-6.mol
5,6-Diamino-1,3-dimethyluracil hydrate Chemical Properties
Melting point 210-214 °C (dec.)(lit.)
Boiling point 243.6±50.0℃ (760 Torr)
density 1.350±0.06 g/cm3 (20 ºC 760 Torr)
Fp 101.1±30.1℃
solubility DMSO, Methanol
pka4.42±0.70(Predicted)
form Solid
color Pale Brown
BRN 157451
EPA Substance Registry System2,4(1H,3H)-Pyrimidinedione, 5,6-diamino-1,3-dimethyl- (5440-00-6)
Safety Information
WGK Germany 3
10-34
MSDS Information
5,6-Diamino-1,3-dimethyluracil hydrate Usage And Synthesis
Chemical PropertiesPale Brown Solid
Uses5,6-Diamino-1,3-dimethyluracil hydrate can be used as reactant involved in the synthesis of biologically active molecules including: 1H-Imidazol-1-yl substituted 8-phenylxanthines for use as adenosine receptor ligands ; Pyrimidinyl purinediones via cyclocondensation ; Theophylline derivatives as adenosine receptor antagonists ; Pteridine analogs for use as monoamine oxidase B and nitric oxide synthase inhibitors ; Fused tricyclic xanthines and Cadmium uraciliminoethylpyridine complexes for use as antiproliferatives against C6 glioma cells6.
Uses5,6-Diamino-1,3-dimethyl Uracil (cas# 5440-00-6) is a compound useful in organic synthesis.
UsesReactant involved in the synthesis of biologically active molecules including:
  • 1H-Imidazol-1-yl substituted 8-phenylxanthines for use as adenosine receptor ligands
  • Pyrimidinyl purinediones via cyclocondensation
  • Theophylline derivatives as adenosine receptor antagonists
  • Pteridine analogs for use as monoamine oxidase B and nitric oxide synthase inhibitors
  • Fused tricyclic xanthines
  • Cadmium uraciliminoethylpyridine complexes for use as antiproliferatives against C6 glioma cells
Purification MethodsIt recrystallises from EtOH. The hydrochloride has m 310o (from MeOH), and the perchlorate has m 246-248o. [UV: Bredereck et al. Chem Ber 92 583 1959, Taylor et al. J Am Chem Soc 77 2243 1955, Beilstein 25 III/IV 4133.]
5,6-Diamino-1,3-dimethyluracil hydrate Preparation Products And Raw materials
Raw materialsCyanoacetic acid
Preparation ProductsISOCAFFEINE

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