Methyl indolyl-3-glyoxylate

Methyl indolyl-3-glyoxylate
  • CAS No.:18372-22-0
Other grades of this product :
Methyl indolyl-3-glyoxylate Basic information
Product Name:Methyl indolyl-3-glyoxylate
Synonyms:α-Oxo-1H-indole-3-acetic Acid Methyl Ester;1H-Indole-3-acetic acid, α-oxo-, Methyl ester;Methyl 2-(indol-3-yl)-2-oxoacetate;Methyl Indol-3-Glyoxylate;Methyl 3-indoleglyoxylate 98%;(1H-Indol-3-yl)-oxo-acetic acid methyl ester;2-(1H-indol-3-yl)-2-keto-acetic acid methyl ester;2-(1H-indol-3-yl)-2-oxoacetic acid methyl ester
CAS:18372-22-0
MF:C11H9NO3
MW:203.19
EINECS:
Product Categories:Indole Derivatives;Indole;Building Blocks;Heterocyclic Building Blocks;Indoles
Mol File:18372-22-0.mol
Methyl indolyl-3-glyoxylate Chemical Properties
Melting point 227-230 °C (lit.)
Boiling point 383.2±15.0 °C(Predicted)
density 1.324±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Acetone, Methanol
pka14.54±0.30(Predicted)
form Solid
color Pale Yellow Fine
Stability:Temperature Sensitive
CAS DataBase Reference18372-22-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
HazardClass IRRITANT
MSDS Information
ProviderLanguage
SigmaAldrich English
Methyl indolyl-3-glyoxylate Usage And Synthesis
Chemical PropertiesPale Yellow Fine Powder
UsesReactant for preparation of sotrastaurin analogs as protein kinase inhibitors 1 Reactant for synthesis of GSK-3 inhibitors 2 Reactant for Diels-Alder cycloaddition 3 Reactant for preparation of a Janus kinase 3 inhibitor 4 Reactant for synthesis of cephalandole alkaloids 5 Reactant for stereoselective preparation of COX-2 inhibitor as anticancer agent 6 Reactant for synthesis of cycloalkene indole carbazole alkaloids via ring-closing metathesis.
UsesMethyl Indolyl-3-glyoxylate (cas# 18372-22-0) is a compound useful in organic synthesis.
Methyl indolyl-3-glyoxylate Preparation Products And Raw materials
Raw materialsIndole-3-glyoxylic acid-->METHYL OXALYL CHLORIDE-->INDOLE-3-GLYOXYLYL CHLORIDE-->Methanol-->HEXAKETOCYCLOHEXANE OCTAHYDRATE-->Indole
Preparation ProductsTryptophol

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