2,4-Dimethoxybenzeneboronic acid

2,4-Dimethoxybenzeneboronic acid
  • CAS No.:133730-34-4
Other grades of this product :
2,4-Dimethoxybenzeneboronic acid Basic information
Uses Uses
Product Name:2,4-Dimethoxybenzeneboronic acid
Synonyms:RARECHEM AH PB 0099;2,4-DIMETHOXYPHENYLBORONIC ACID;2,4-DIMETHOXYBENZENEBORONIC ACID;AKOS BRN-0063;2,4-Dimethoxyphenylboronic Acid (contains varying amounts of Anhydride);2,4-Dimethoxyphenylboronic acid ,98%;2,4-Dimethoxybenzeneboronic acid,97%;2,4-DIMETHOXYBENZENEBORONIC ACID,98+%
CAS:133730-34-4
MF:C8H11BO4
MW:181.98
EINECS:679-695-3
Product Categories:Aryl Boronic Acids;Boronic Acids and Derivatives;Boronic acids;Chemical Synthesis;Disubstituted Aryl Boronic Acids;Organometallic Reagents;blocks;BoronicAcids;Substituted Boronic Acids;Boronic Acid;Alkoxy;Aryl;Organoborons;B (Classes of Boron Compounds);Boronic Acids;Boronic Acids and Derivatives
Mol File:133730-34-4.mol
2,4-Dimethoxybenzeneboronic acid Chemical Properties
Melting point 125-127 °C (lit.)
Boiling point 361.1±52.0 °C(Predicted)
density 1.19±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility soluble in Methanol
pka8.98±0.58(Predicted)
form powder to crystal
color White to Dark green
BRN 4744213
CAS DataBase Reference133730-34-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 37/39-26-36/37-24/25
WGK Germany 3
Hazard Note Irritant/Keep Cold
HazardClass IRRITANT
HS Code 29420000
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
2,4-Dimethoxybenzeneboronic acid Usage And Synthesis
Uses

2,4-Dimethoxyphenylboronic acid can be used:

•  As a reactant in meatal-catalyzed Suzuki−Miyaura cross-coupling reaction.

•  To prepare hydroxy(trimethoxy)phenanthrene by cross-coupling with bromo(benzyloxy)methoxybenzaldehyde followed by condensation and debenzylation reaction.

• To synthesize 2,4-dimethoxy-1-(trifluoromethyl)benzene via Cu-catalyzed trifluoromethylation reaction.

Uses

Reactant for:

• Suzuki-Miyaura and Negishi couplings.

Chemical Propertieswhite to beige or pink moist powder
Usessuzuki reaction
Uses2,4-Dimethoxyphenylboronic acid can be used:
  • As a reactant in meatal-catalyzed Suzuki?Miyaura cross-coupling reaction.
  • To prepare hydroxy(trimethoxy)phenanthrene by cross-coupling with bromo(benzyloxy)methoxybenzaldehyde followed by condensation and debenzylation reaction.
  • To synthesize 2,4-dimethoxy-1-(trifluoromethyl)benzene via Cu-catalyzed trifluoromethylation reaction.
2,4-Dimethoxybenzeneboronic acid Preparation Products And Raw materials
Preparation ProductsMETHYL 2,4-DIMETHOXYBENZOATE

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