(-)-Di-p-toluoyl-L-tartaric acid

CAS No.：32634-66-5

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(-)-Di-p-toluoyl-L-tartaric acid Basic information

Uses

Product Name:	(-)-Di-p-toluoyl-L-tartaric acid
Synonyms:	(-)-Ditoluoyl-(L)-tartaric acid monohydrate;Di-4-Toluoyl-L-tartaric acid;(-)-2,3-DI-P-TOLUOYL-L-TARTARIC ACID;Di-p-Toluyl-L-Tartaric Acid Anhydrous;(-)-DI-O,O'-P-TOLUOYL-L-TARTARIC ACID;Di-Para-Toluoyl-D-TartaricAcid,Anhydrous;Di-Para-Toluoyl-L-TartaricAcid;Di-P-Toluoyl-L-TartaricAcid(Anhydrous)
CAS:	32634-66-5
MF:	C20H18O8
MW:	386.35
EINECS:	251-131-7
Product Categories:	chiral;Carboxylic Acids (Chiral);Chiral Building Blocks;for Resolution of Bases;Optical Resolution;Synthetic Organic Chemistry;Pharmaceutical Intermediates;FINE Chemical & INTERMEDIATES;Chiral Compounds;Miscellaneous;CHIRAL CHEMICALS;Hydroxy Acids & Deriv.;Carboxylic AcidsAsymmetric Synthesis;Chiral Building Blocks;Chiral Compound;Inhibitors;Chiral Resolution Reagents;Chiral Resolving Reagents;Organic Building Blocks
Mol File:	32634-66-5.mol

(-)-Di-p-toluoyl-L-tartaric acid Chemical Properties

Melting point	169-171 °C(lit.)
alpha	-142 º (c=10, EtOH)
Boiling point	432.57°C (rough estimate)
density	1.3084 (rough estimate)
refractive index	-139 ° (C=1, EtOH)
storage temp.	Store below +30°C.
solubility	Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
pka	1.46±0.25(Predicted)
form	Crystalline Powder
color	White to yellow
optical activity	[α]20/D 138°, c = 1 in ethanol
Water Solubility	soluble
BRN	2022481
CAS DataBase Reference	32634-66-5(CAS DataBase Reference)
EPA Substance Registry System	Butanedioic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, [R-(R,R)]- (32634-66-5)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	22-24/25-36/37-26
WGK Germany	3
TSCA	T
HS Code	29181300

MSDS Information

Provider	Language
(-)-Di-p-toluoyl-L-tartaric acid	English
SigmaAldrich	English
ACROS	English
ALFA	English

(-)-Di-p-toluoyl-L-tartaric acid Usage And Synthesis

Uses	(-)-di-p-toluoyl-l-tartaric acid can be used as a chiral resolving agent for the resolution of the racemic bases to isolate the (-)-enantiomeric forms.
Chemical Properties	white to light yellow crystal powde
Uses	Escitalopram intermediate
Uses	(-)-O,O’-Di-p-toluoyl-L-tartaric Acid is a useful reagent for the preparation of the upadacitinib salt compound.
Uses	Inhibitor of enzyme
General Description	(-)-O,O′-Di-p-toluoyl-L-tartaric acid is a O,O′-diacyl tartaric acid derivative that can be prepared by the resolution of its racemate in the presence of cinchonine.

(-)-Di-p-toluoyl-L-tartaric acid Preparation Products And Raw materials

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