1-Bromopinacolone

1-Bromopinacolone
  • CAS No.:5469-26-1
Other grades of this product :
1-Bromopinacolone Basic information
Product Name:1-Bromopinacolone
Synonyms:omega-brompinakolin;Pivaloylmethyl bromide;pivaloylmethylbromide;tert-Butyl Bromomethyl ketone;2-Butanone, 1-bromo-3,3-dimethyl-;1-BROMOPINACOLONE, 97+%;1-BROMOPINACOLONE, TECH., CA. 90%;Bromopinacolone
CAS:5469-26-1
MF:C6H11BrO
MW:179.05
EINECS:226-794-0
Product Categories:Building Blocks;C3 to C6;Carbonyl Compounds;Chemical Synthesis;Ketones;Organic Building Blocks
Mol File:5469-26-1.mol
1-Bromopinacolone Chemical Properties
Melting point -10 °C (lit.)
Boiling point 188-194 °C (lit.)
density 1.331 g/mL at 25 °C (lit.)
refractive index n20/D 1.466(lit.)
Fp 195 °F
storage temp. -20°C
solubility Chloroform, Methanol
form Liquid
color Clear pale yellow to yellow-brownish
Water Solubility Insoluble in water.
BRN 506485
InChIKeySAIRZMWXVJEBMO-UHFFFAOYSA-N
CAS DataBase Reference5469-26-1(CAS DataBase Reference)
NIST Chemistry Reference2-Butanone, 1-bromo-3,3-dimethyl-(5469-26-1)
Safety Information
Hazard Codes Xi,F
Risk Statements 36/37/38
Safety Statements 26-37/39
RIDADR 1224
WGK Germany 3
RTECS EL7010000
8-10-21
Hazard Note Irritant/Flammable
HazardClass 3.2
PackingGroup III
HS Code 29147000
MSDS Information
ProviderLanguage
Bromomethyl tert-butyl ketone English
SigmaAldrich English
ACROS English
ALFA English
1-Bromopinacolone Usage And Synthesis
Chemical Propertiesclear pale yellow to yellow-brownish liquid
Uses1-Bromopinacolone is used as an iIntermediate for triazole compounds ( a five-membered ring structure compound contains three nitrogens and two carbons in the ring) which have biological activities such as antiviral, antibacterial, antifungal and antituberculous.
General Description1-Bromopinacolone is an α-bromoketone-aldehyde. Coupling of 1-bromopinacolone with various aldehyde electrophiles catalyzed by SmI2 has been reported. It acts as reversible competitive inhibitor for acetylcholinesterase, during hydrolysis of acetylcholine.

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