2-QUINOXALINECARBONYL CHLORIDE

CAS No.：54745-92-5

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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2-QUINOXALINECARBONYL CHLORIDE Basic information

Product Name:	2-QUINOXALINECARBONYL CHLORIDE
Synonyms:	2-QUINOXALOYL CHLORIDE;2-QUINOXALINECARBONYL CHLORIDE;TIMTEC-BB SBB000309;quinoxaline-2-carbonyl chloride;2-Quinoxalinecarbonyl chloride (7CI, 9CI);2-Quinoxaloyl chloride,97+%;2-(Chlorocarbonyl)quinoxaline, 1,4-Benzodiazine-2-carbonyl chloride;2-Quinoxoyl chloride
CAS:	54745-92-5
MF:	C9H5ClN2O
MW:	192.6
EINECS:	259-315-9
Product Categories:	ACIDHALIDE
Mol File:	54745-92-5.mol

2-QUINOXALINECARBONYL CHLORIDE Chemical Properties

Melting point	113-115 °C (lit.)
storage temp.	2-8°C
form	Liquid
color	Clear colorless to pale yellow
CAS DataBase Reference	54745-92-5

Safety Information

Hazard Codes	C
Risk Statements	34
Safety Statements	26-27-28-36/37/39-45
RIDADR	UN 3261 8/PG 2
WGK Germany	3
HazardClass	8
PackingGroup	III
HS Code	2933998090

MSDS Information

Provider	Language
ACROS	English
SigmaAldrich	English

2-QUINOXALINECARBONYL CHLORIDE Usage And Synthesis

Chemical Properties	Off-white to tan crystalline powder
Uses	Reactant involved in the synthesis of a variety of inhibitors including: Gelatinase inhibitors for cancer treatments mGluR5 non-competitve antagonists Heterocyclic analogs used as SIRT1 activators 3rd Generation multidrug resistance modulators Reactant involved in preparation of PET ligants for breast cancer resistance protein imaging
General Description	2-Quinoxaloyl chloride reacts with chiral α-hydroxy carboxylic acids to yield UV and fluorescent derivatives.

2-QUINOXALINECARBONYL CHLORIDE Preparation Products And Raw materials

Raw materials	Ethanol-->Hydrochloric acid-->Ethyl acetate-->Thionyl chloride-->PETROLEUM ETHER-->Toluene-->Sulfuryl chloride-->Oxalyl chloride-->o-Phenylenediamine-->Potassium dichromate-->Carbon-->2-Methylquinoxaline-->SODIUM DIHYDROXYTARTRATE
Preparation Products	N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide

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