NIPRADILOL

NIPRADILOL
  • CAS No.:81486-22-8
Other grades of this product :
NIPRADILOL Basic information
Product Name:NIPRADILOL
Synonyms:K 351;3,4-Dihydro-8-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-2H-1-benzopyran-3-ol 3-nitrate;Hypadil;Nipradolol;Nipranol;2H-1-Benzopyran-3-ol, 3,4-dihydro-8-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-, 3-nitrate;3,4-Dihydro-8-(2-hydroxy-3-(isopropylamino)propoxy)-2H-1-benzopyran-3-ol 3-nitrate;3,4-Dihydro-8-(2-hydroxy-3-isopropylamino)propoxy-3-nitroxy-2H-1-benzopyran
CAS:81486-22-8
MF:C15H22N2O6
MW:326.35
EINECS:
Product Categories:API
Mol File:81486-22-8.mol
NIPRADILOL Chemical Properties
Melting point 110-122℃
Boiling point 464.39°C (rough estimate)
density 1.1829 (rough estimate)
refractive index 1.6280 (estimate)
Safety Information
ToxicityLD50 i.v. in mice, rats: 74.0, 73.0 mg/kg; orally in mice: 540 mg/kg (Shiratsuchi, 1988)
MSDS Information
NIPRADILOL Usage And Synthesis
DescriptionNipradilol is a beta-blocker with vasodilatory activity. As an antihypertensive nipradilol decreases systemic/pulmonary arterial blood pressure, heart rate, cardiac output and left ventricular volume without causing tachycardia. Nipradilol is also reported to have antiangina activity in dogs.
OriginatorKowa (Japan)
UsesNipradolol is a β-adrenoceptor blocking agent with antihypertensive properties.?Nipradolol is used as an?anti-glaucomatous agent.
Brand nameHypadil

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