Chlorosulfonyl isocyanate

Chlorosulfonyl isocyanate
  • CAS No.:1189-71-5
Other grades of this product :
Chlorosulfonyl isocyanate Basic information
Product Name:Chlorosulfonyl isocyanate
Synonyms:N-Carbonylsulfamyl chloride, CSI;N-(Oxomethylidene)sulfamoyl chloride;N-Chlorosulphonyl isocyanate;[(Chlorosulfonyl)imino]methanone;Chlorosulfonyl isocyanate ,99%;Chlorosulfonyl isocyanate,N-Carbonylsulfamyl chloride, CSI;Chlorosulfonyl isocy;sulfurisocyanatidic chloride
CAS:1189-71-5
MF:CClNO3S
MW:141.53
EINECS:214-715-2
Product Categories:Sulfur Compounds (for Synthesis);Synthetic Organic Chemistry;Pharmaceutical Intermediates;Cyanogen chloride derivatives;Hydrocyanic acid derivatives
Mol File:1189-71-5.mol
Chlorosulfonyl isocyanate Chemical Properties
Melting point -44 °C (lit.)
Boiling point 107 °C (lit.)
density 1.626 g/mL at 25 °C (lit.)
vapor pressure 5.57 psi ( 20 °C)
refractive index n20/D 1.447(lit.)
Fp >110°C
storage temp. 2-8°C
form Crystals, Crystalline Powder or Granules
Specific Gravity1.626 (20℃)
color White
Water Solubility reacts violently exothermic
BRN 1237247
CAS DataBase Reference1189-71-5(CAS DataBase Reference)
EPA Substance Registry SystemSulfuryl chloride isocyanate (1189-71-5)
Safety Information
Hazard Codes C
Risk Statements 14-22-34-42-20/22
Safety Statements 23-26-30-36/37/39-45
RIDADR UN 3265 8/PG 2
WGK Germany 3
10-21-19
HazardClass 8
PackingGroup II
HS Code 28510080
ToxicityLD50 orally in Rabbit: 640 mg/kg
MSDS Information
ProviderLanguage
N-Carbonylsulfamyl chloride English
ACROS English
SigmaAldrich English
Chlorosulfonyl isocyanate Usage And Synthesis
Chemical PropertiesClear liquid, colourless
UsesChlorosulfonyl isocyanate, a highly reactive chemical for chemical synthesis, is used as an intermediate used for production of antibiotics (Cefuroxime, penems), polymers as well as agrochemicals. Product Data Sheet
UsesEmployed in a regio- and diastereoselective introduction of a protected amino group in a synthesis of chiral, polyhydroxylated piperidines. Generation of ureas from amino groups in a synthesis of benzimidazolones.
General DescriptionChlorosulfonyl isocyanate reacts with hydrocarbon alkenes via stepwise dipolar pathway to give N-chlorosulfonyl-β-lactams.

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