Product

2-Chloropyrimidine-5-carboxylic acid

CAS No.：374068-01-6

Other grades of this product :

2-Chloropyrimidine-5-carboxylic acid Basic information

Product Name:	2-Chloropyrimidine-5-carboxylic acid
Synonyms:	2-CHLORO-5-CARBOXYPYRIMIDINE;2-CHLORO-PYRIMIDINE-5-CARBOXYLIC ACID;5-Carboxy-2-chloropyrimidine;5-Carboxy-2-chloropyrimidine, 5-Carboxy-2-chloro-1,3-diazine;SA023574;5-Pyrimidinecarboxylicacid, 2-chloro-;CML-011;101789
CAS:	374068-01-6
MF:	C5H3ClN2O2
MW:	158.54
EINECS:
Product Categories:	Heterocycle-Pyrimidine series;Building Blocks;Carboxylic Acids;Pyrazines, Pyrimidines & Pyridazines;Carboxylic Acids;Pyrimidine;Pyrazines, Pyrimidines & Pyridazines
Mol File:	374068-01-6.mol

2-Chloropyrimidine-5-carboxylic acid Chemical Properties

Melting point	126-131 °C
Boiling point	411.4±18.0 °C(Predicted)
density	1.579±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
form	Powder or Crystalline Powder
pka	2.51±0.10(Predicted)
color	White to off-white

Safety Information

HS Code

29335990

MSDS Information

2-Chloropyrimidine-5-carboxylic acid Usage And Synthesis

Uses	2-Chloropyrimidine-5-carboxylic acid is carboxylic acid organic compounds, mainly used as pharmaceutical intermediates.
Uses	2-Chloropyrimidine-5-carboxylic Acid is a compound involved in the synthesis of novel (6-aminopyridin-3-yl)(4-(pyridin-2-yl)piperazin-1-yl) methanone derivatives as TRPV4 antagonists for the treatment of pain.

2-Chloropyrimidine-5-carboxylic acid Preparation Products And Raw materials

Raw materials

Ethanol-->Sodium hydroxide-->Hydrochloric acid-->Ethyl acetate-->Tetrahydrofuran-->Acetic acid-->Sodium-->Phosphorus oxychloride-->Government regulation-->Sodium sulfate-->Sodium chloride-->Benzene-->Urea-->Dimethyl sulfate-->N,N-Dimethylaniline-->Ethyl formate-->Triethylamine hydrochloride-->Ethyl 3-ethoxypropionate

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